(5-Methyl-3-phenyl-1,2-oxazol-4-yl)-pyrrol-1-ylmethanone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: (5-Methyl-3-phenyl-1,2-oxazol-4-yl)-pyrrol-1-ylmethanone
• 化学式: C₁₅H₁₂N₂O₂
• 分子量: 252.27
• InChiKey: DMDXFTXPBFZQBR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  48
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Flavivirus Inhibitors and Methods of Their Use
  申请人：Padmanabhan Radhakrishnan

  公开号：US20140038962A1

  公开（公告）日：2014-02-06

  Methods of treating, preventing, and/or ameliorating a Flavivirus infection in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a Flavivirus inhibitor, e.g., a Flavivirus serine protease inhibitor. These methods are useful in treating, preventing, and/or ameliorating Flavivirus infections such as, for example, West Nile Virus, Dengue Virus, and Japanese Encephalitis Virus.
• US8906937B2
  申请人：——

  公开号：US8906937B2

  公开（公告）日：2014-12-09
• [FR] INHIBITEUR DE FLAVIVIRUS ET PROCÉDÉS D'UTILISATION DE CEUX-CI
  申请人：UNIV GEORGETOWN

  公开号：WO2010039538A2

  公开（公告）日：2010-04-08

  Methods of treating, preventing, and/or ameliorating a Flavivirus infection in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a Flavivirus inhibitor, e.g., a Flavivirus serine protease inhibitor. These methods are useful in treating, preventing, and/or ameliorating Flavivirus infections such as, for example, West Nile Virus, Dengue Virus, and Japanese Encephalitis Virus.