2-Decanamidopentanedioic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Decanamidopentanedioic acid
• 英文别名: 2-(decanoylamino)pentanedioic acid
• 化学式: C₁₅H₂₇NO₅
• 分子量: 301.38
• InChiKey: OBACDZMAJJOBJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  21
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  104
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Organic compounds
  申请人：Givaudan S.A.

  公开号：US10836712B2

  公开（公告）日：2020-11-17

  A flavour composition comprising a compound according to the formula (I) or edible salts thereof, wherein R1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and NR2R3, in which R3 is H or together with R2 and the N-atom to which they are attached, a 5-membered ring, is a residue of an amino acid, in particular a proteinogenic amino acid, ornithine, gamma-aminobutyric acid or beta alanine, or a 1-amino cycloalkyl carboxylic acid.

  一种包含符合式(I)的化合物或其可食用盐的风味组合物，其中R1是含有6至20个碳原子的烷基残基，或者含有9至25个碳原子且具有1至6个双键的烯烃残基，R1与其连接的羰基一起是羧酸的残基，NR2R3中，R3为H或与R2和它们连接的N原子一起是一个5元环的残基，是一种氨基酸的残基，特别是一种蛋白质原性氨基酸、鸟氨酸、γ-氨基丁酸或β-丙氨酸，或者是一种1-氨基环烷基羧酸的残基。
• N-Acyl-Amino Acid Derivatives for Improvement of the Flavour Profile Edible Compositions
  申请人：Givaudan S.A.

  公开号：US20150086694A1

  公开（公告）日：2015-03-26

  The use of a compound according to formula (I) or the edible salts thereof in an edible composition to mask or modulate an undesired taste or off-taste contained in the edible composition wherein R 1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R 1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and NR 2 R 3 , in which R 3 is H or together with R 2 and the N-atom to which they are attached, a 5-membered ring, is a residue of an amino acid, in particular a proteinogenic amino acid, ornithine, gamma-aminobutyric acid or beta alanine, or a 1-amino cycloalkyl carboxylic acid.

  根据公式（I）或其可食用盐在可食用组合物中的使用，以掩盖或调节可食用组合物中所含的不良味道或异味，其中R1是含6至20个碳原子的烷基残基，或含有1至6个双键的9至25个碳原子的烯烃残基，R1与其附着的羰基基团一起是羧酸的残基，而NR2R3中，R3为H或与R2和它们所附着的N原子一起，形成一个5元环，是氨基酸的残基，特别是蛋白质原氨基酸、鸟氨酸、γ-氨基丁酸或β-丙氨酸，或1-氨基环烷基羧酸的残基。
• Cosmestic composition
  申请人：UNILEVER PLC

  公开号：EP0572167A1

  公开（公告）日：1993-12-01

  A composition suitable for topical application to mammalian skin and hair for inducing, maintaining or increasing hair growth comprises a hair growth promoter chosen from glutamic acid derivatives and salts thereof. The composition preferably also comprises an activity enhancer which may be chosen from hair growth stimulants, penetration enhancers and cationic polymers.

  一种适用于哺乳动物皮肤和毛发的外用组合物，可诱导、维持或增加毛发生长，其中包括一种毛发生长促进剂，选自谷氨酸衍生物及其盐类。该组合物最好还包含一种活性增强剂，它可以选自毛发生长刺激剂、渗透增强剂和阳离子聚合物。
• METHOD FOR PRODUCING N-ACYL-AMINO GROUP-CONTAINING COMPOUND
  申请人：AJINOMOTO CO., INC.

  公开号：EP3778912A1

  公开（公告）日：2021-02-17

  The present invention provides a method of efficiently producing an N-acyl-amino group-containing compound by an enzymatic method. Specifically, the present invention provides a method of producing an N-acyl-amino group-containing compound, comprising producing the N-acyl-amino group-containing compound by reacting an amino group-containing compound with a carboxyl group-containing compound in the presence of an enzyme having an ability to bond a carboxyl group and an amino group in an ATP dependent manner to form an amide bond.

  本发明提供了一种通过酶法高效生产含 N-酰基氨基化合物的方法。具体地说，本发明提供了一种生产含 N-酰基-氨基化合物的方法，包括在一种酶的存在下，使一种含氨基的化合物与一种含羧基的化合物反应生成含 N-酰基-氨基化合物，该酶具有以依赖 ATP 的方式键合羧基和氨基以形成酰胺键的能力。
• Molecularly imprinted polymer for selectively trapping odorous molecules
  申请人：L'ORÉAL

  公开号：US10772823B2

  公开（公告）日：2020-09-15

  The invention relates to the use of molecularly imprinted polymer(s) or MIPs, of odorous molecule(s), as deodorant agent in particular for selectively trapping molecules that are the cause of human body odour. More particularly by using MIPs which may be obtained via polymerization, preferably via radical polymerization, of a mixture of: i) optionally one or more polymerization initiator(s); ii) one or more functional monomer(s); iii) one or more crosslinking agent(s); and iv) one or more porogenic solvent(s); it being understood that the polymerization a) or b) is performed in the presence v) of one or more “templates” of target molecule(s) responsible for human body odour. Another subject of the invention concerns a process for preparing MIPs as defined previously, MIPs obtained via this process, and a cosmetic composition comprising at least one MIP as defined previously. Unexpectedly, it appears that the MIPs make it possible to specifically trap precursors of odorous molecules and odorous molecules that may be used in cosmetic formulations, especially those that are the cause of the unpleasant odour of sweat.

  本发明涉及气味分子的分子印迹聚合物或 MIPs 作为除臭剂的用途，特别是用于选择性地捕获导致人体气味的分子。更具体地说，MIPs 可通过以下混合物的聚合（最好是自由基聚合）获得：i) 一种或多种聚合引发剂；ii) 一种或多种功能性单体；iii) 一种或多种交联剂；iv) 一种或多种致孔溶剂。本发明的另一个主题涉及前文定义的 MIP 制备工艺、通过该工艺获得的 MIP 以及包含至少一种前文定义的 MIP 的化妆品组合物。令人意想不到的是，MIPs 似乎可以专门捕获气味分子的前体和可用于化妆品配方的气味分子，特别是那些导致难闻汗味的分子。