6-乙酰氧基蒽[9,1-BC]呋喃-2-酮 | 101438-98-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 中文名称: 6-乙酰氧基蒽[9,1-BC]呋喃-2-酮
• 英文名称: 6-acetoxy-anthra[9,1-bc]furan-2-one
• 英文别名: 6-Acetoxy-anthra[9,1-bc]furan-2-on；(14-Oxo-15-oxatetracyclo[7.6.1.02,7.013,16]hexadeca-1(16),2,4,6,8,10,12-heptaen-8-yl) acetate
• CAS: 101438-98-6
• 化学式: C₁₇H₁₀O₄
• 分子量: 278.264
• InChiKey: DVPGPGBMHMPPAJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  6-乙酰氧基蒽[9,1-BC]呋喃-2-酮 、 alkaline earth salt of/the/ methylsulfuric acid 生成 9,10-dihydroxy-anthracene-1-carboxylic acid
  参考文献：
  名称：

  A possible mode of the specific recognition of nucleic acids by proteins

  摘要：

  Seven sets of protein target sites, which occur in several gene promoters, have been analyzed. The results suggest that there is a possible mode of specific recognition of double-helical nucleic acids by proteins, This recognition mode is related to a special topological property of double-helical DNA, which is termed base spatial pattern (BSP) of DNA segment. BSP is the spatial topological property determined only by the spatial arrangement of the bases on double-helical DNA segment.

  DOI：

  10.1007/bf02900469
• 作为产物：
  描述：

  9,10-二氧代-9,10-二氢-蒽-1-羧酸 在 sodium dithionite 作用下， 生成 6-乙酰氧基蒽[9,1-BC]呋喃-2-酮
  参考文献：
  名称：

  A possible mode of the specific recognition of nucleic acids by proteins

  摘要：

  Seven sets of protein target sites, which occur in several gene promoters, have been analyzed. The results suggest that there is a possible mode of specific recognition of double-helical nucleic acids by proteins, This recognition mode is related to a special topological property of double-helical DNA, which is termed base spatial pattern (BSP) of DNA segment. BSP is the spatial topological property determined only by the spatial arrangement of the bases on double-helical DNA segment.

  DOI：

  10.1007/bf02900469

文献信息

• Activation of JNK, p38 and ERK mitogen-activated protein kinases by chromium(VI) is mediated through oxidative stress but does not affect cytotoxicity
  作者：Show-Mei Chuang、Geou-Yarh Liou、Jia-Ling Yang

  DOI：10.1093/carcin/21.5.491

  日期：2000.8.1