1-Hexadecyl-3-methyl-1H-benzo[d]imidazol-3-ium bromide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 1-Hexadecyl-3-methyl-1H-benzo[d]imidazol-3-ium bromide
• 英文别名: 1-hexadecyl-3-methylbenzimidazol-3-ium;bromide
• 化学式: C24H41BrN2
• 分子量: 437.5
• InChiKey: GYHVMZIUFDYDKK-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  3.95
• 重原子数：
  27
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  8.8
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Methods to control infection using new generation small molecule growth inhibitors
  申请人：Ohio State Innovation Foundation

  公开号：US11478454B2

  公开（公告）日：2022-10-25

  Disclosed herein are methods of treating a subject with a bacterial infection, or preventing a bacterial infection, comprising administering to the subject an effective amount of at least one compound, or a derivative thereof, having the formula of SM1, SM3, SM4, or SM5. Also described are methods of inhibiting bacterial growth in a plant comprising contacting the plant with an effective amount of at least one compound, or a derivative thereof, having the formula of SM1, SM3, SM4, or SM5. The methods are effective against an array of bacterial pathogens in various animals and plants.

  本文公开了治疗细菌感染或预防细菌感染的方法，包括向受试者施用有效量的至少一种具有 SM1、SM3、SM4 或 SM5 式的化合物或其衍生物。 还描述了抑制植物中细菌生长的方法，包括用有效量的至少一种具有 SM1、SM3、SM4 或 SM5 式的化合物或其衍生物与植物接触。 这些方法对各种动物和植物中的一系列细菌病原体有效。
• METHODS TO CONTROL INFECTION USING NEW GENERATION SMALL MOLECULE GROWTH INHIBITORS
  申请人：Ohio State Innovation Foundation

  公开号：US20200405691A1

  公开（公告）日：2020-12-31

  Disclosed herein are methods of treating a subject with a bacterial infection, or preventing a bacterial infection, comprising administering to the subject an effective amount of at least one compound, or a derivative thereof, having the formula of SM1, SM3, SM4, or SM5. Also described are methods of inhibiting bacterial growth in a plant comprising contacting the plant with an effective amount of at least one compound, or a derivative thereof, having the formula of SM1, SM3, SM4, or SM5. The methods are effective against an array of bacterial pathogens in various animals and plants.