N-(3-Chlorophenyl)-2-[3-oxo-1-(2-thienylsulfonyl)-1,2,3,4-tetrahydro-2-quinoxalinyl]acetamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-(3-Chlorophenyl)-2-[3-oxo-1-(2-thienylsulfonyl)-1,2,3,4-tetrahydro-2-quinoxalinyl]acetamide
• 英文别名: N-(3-chlorophenyl)-2-(3-oxo-1-thiophen-2-ylsulfonyl-2,4-dihydroquinoxalin-2-yl)acetamide
• 化学式: C₂₀H₁₆ClN₃O₄S₂
• 分子量: 461.9
• InChiKey: JIKPZSZRAFFRLW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  132
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• 2-Quinoxalinone derivatives as bradykinin antagonists and novel compounds
  申请人：Su Dai-Shi

  公开号：US20050020591A1

  公开（公告）日：2005-01-27

  2-Quinoxalinone derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.

  2-喹喔啉酮衍生物是布雷金肽B1拮抗剂或逆向激动剂，可用于治疗或预防与布雷金肽B1途径相关的症状，如疼痛和炎症。
• (2-((2-alkoxy)-phenyl)-cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives
  申请人：Giblin Paul Gerard Martin

  公开号：US20050239802A1

  公开（公告）日：2005-10-27

  Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein A, R 1 , R 2 , R x , R 8 , R 9 and n are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.

  公式（I）的化合物或其药学上可接受的衍生物：其中A，R1，R2，Rx，R8，R9和n如规范中所定义，制备这种化合物的过程，包括这种化合物的制药组合物以及在医学中使用这种化合物的用途。
• Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same
  申请人：——

  公开号：US20020110530A1

  公开（公告）日：2002-08-15

  An antimicrobial compound, composition containing such compound, and method of use of the same for reducing the presence of microorganism on a substrate or in a fluid environment comprising an antimicrobial effective carrier and one or more essential antimicrobial compounds including non-halogenated naphthol compounds.

  一种抗菌化合物、含有这种化合物的组合物及其使用方法，用于减少基质或流体环境中微生物的存在，该组合物包含一种抗菌有效载体和一种或多种基本抗菌化合物（包括非卤代萘酚化合物）。
• Agent for suppressing transfer of odor and taste originating from a diacetal a diacetal composition comprising the agent for suppressing transfer of odor and taste a polyolefin nucleating agent comprising the composition a polyolefin resin composition and a molded product comprising the nucleating agent
  申请人：Ishikawa Masahide

  公开号：US20050171230A1

  公开（公告）日：2005-08-04

  Disclosed are an agent for suppressing transfer of odor and taste originating from a diacetal such as dibenzylidene sorbitol, comprising (B) an aliphatic alcohol or an aliphatic carboxylic acid containing at least one hydroxyl group, or comprising component (B) and (C) at least one member selected from the group consisting of specific sulfuric ester salts, saturated or unsaturated fatty acid alkali metal salts and aliphatic amines; a diacetal composition comprising the suppressing agent and the diacetal; a resin composition and a molded product comprising the diacetal composition and a polyolefin resin; and a method for suppressing transfer of odor and taste originating from the diacetal, or a method for suppressing aldehyde generation by thermal decomposition of the diacetal, comprising using the suppressing agent.

  本发明公开了一种用于抑制源自二缩醛（如二亚苄基山梨醇）的气味和味道转移的制剂，包括(B)脂肪醇或含有至少一个羟基的脂肪族羧酸，或包括组分(B)和(C)至少一个选自特定硫酸酯盐、饱和或不饱和脂肪酸碱金属盐和脂肪族胺组成的组的成员；由抑制剂和二缩醛组成的二缩醛组合物；由二缩醛组合物和聚烯烃树脂组成的树脂组合物和模塑产品；以及抑制二缩醛产生的气味和味道转移的方法，或抑制二缩醛热分解产生醛的方法，包括使用抑制剂。
• US6838583B2
  申请人：——

  公开号：US6838583B2

  公开（公告）日：2005-01-04