3-Chloro-4-(2-methylpropoxy)-4-oxobut-2-enoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-Chloro-4-(2-methylpropoxy)-4-oxobut-2-enoic acid
• 英文别名: 3-chloro-4-(2-methylpropoxy)-4-oxobut-2-enoic acid
• 化学式: C₈H₁₁ClO₄
• 分子量: 206.62
• InChiKey: QLBHBTZBKDJYQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• COMPOSITION THAT CAN BE CURED BY POLYMERISATION FOR THE PRODUCTION OF BIODEGRADABLE, BIOCOMPATIBLE, CROSS-LINKABLE POLYMERS ON THE BASIS OF POLYVINYL ALCOHOL
  申请人：Liska Robert

  公开号：US20100303804A1

  公开（公告）日：2010-12-02

  The present invention relates to a polymerization-curable composition for the preparation of biodegradable, biocompatible, cross-linked polymers on the basis of polyvinyl alcohol comprising: 5 to 100% by weight of (a) vinyl ester monomer(s) of one of the general formulas (I) to (III): wherein X is oxygen, sulfur, nitrogen, or phosphorus; n is 1 to 1000, at least 20% of the n being ≧2; the R 1 are selected from hydrogen; straight, branched or cyclic, saturated or unsaturated, n-valent hydrocarbon groups having 1 to 30 carbon atoms, which optionally have heteroatoms and are optionally substituted with one or more substituents selected from —OH, —COON, —CN, —CHO, and ═O, and n-valent radicals of biodegradable, biocompatible oligomers and polymers; m is an integer from 1 to 5; the R 2 are selected from hydrogen, —OH, ═O, and the options listed for R 1 ; and the R 3 are selected from hydrogen, —OH, and the options listed for R 1 ; 0 to 50% by weight of ethylenically unsaturated co-monomers; 0 to 10% by weight of (a) polymerization initiator(s); and 0 to 95% by weight of solvent(s).

  本发明涉及一种用于制备基于聚乙烯醇的可生物降解、生物相容、交联聚合物的聚合固化组合物，包括：按重量计5至100%的(a)乙烯酸酯单体，其具有下列通式(I)至(III)之一： 其中X为氧、硫、氮或磷；n为1至1000，n的至少20%为≧2；R 1 选自氢；直链、支链或环状、饱和或不饱和、含有1至30个碳原子的n价碳氢基团，该基团可选地具有杂原子，并可选地被选自—OH、—COON、—CN、—CHO和═O的一个或多个取代基以及生物降解、生物相容寡聚物和聚合物的n价基团取代；m为1至5的整数；R 2 选自氢、—OH、═O以及R 1 中列出的选项；R 3 选自氢、—OH以及R 1 中列出的选项；按重量计0至50%的乙烯基不饱和共聚单体；按重量计0至10%的(a)聚合引发剂；按重量计0至95%的溶剂。
• THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE
  申请人：Synthes GmbH

  公开号：EP2764049B1

  公开（公告）日：2016-08-17
• US8999323B2
  申请人：——

  公开号：US8999323B2

  公开（公告）日：2015-04-07
• US9623145B2
  申请人：——

  公开号：US9623145B2

  公开（公告）日：2017-04-18
• US9814801B2
  申请人：——

  公开号：US9814801B2

  公开（公告）日：2017-11-14