3-((E)-oct-2-en-1-yl)dihydrofuran-2,5-dione | 81949-84-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-((E)-oct-2-en-1-yl)dihydrofuran-2,5-dione
• 英文别名: trans-3-(2-octen-1-yl)succinic anhydride；3-[(E)-oct-2-en-1-yl]oxolane-2,5-dione；3-oct-2-enyldihydrofuran-2,5-dione；2-Octenylsuccinic Anhydride；3-[(E)-oct-2-enyl]oxolane-2,5-dione
• CAS: 81949-84-0
• 化学式: C₁₂H₁₈O₃
• 分子量: 210.273
• InChiKey: WSGFXVFLWVXTCJ-VOTSOKGWSA-N

物化性质

• 物理描述：
  Liquid
• 熔点：
  8-12°C

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-((E)-oct-2-en-1-yl)dihydrofuran-2,5-dione 生成 α-Hexyl-γ-methylcarboxy-butyrolacton
  参考文献：
  名称：

  BROIS, S. J.;GUTIERREZ, A.

  摘要：

  DOI：
• 作为产物：
  描述：

  辛烯 、 马来酸酐 以90%的产率得到
  参考文献：
  名称：

  ALIEV N. A.; ALIEV Z. Z.; SHAXGELDIEV M. A., AZERB. XIM. ZH., 1978, HO 3, 61-63

  摘要：

  DOI：

文献信息

• Laundry Care Composition Comprising Carboxylate Dye
  申请人：Milliken & Company

  公开号：US20150080561A1

  公开（公告）日：2015-03-19

  The present invention relates to laundry care compositions comprising carboxylate dyes. The laundry care compositions can be laundry detergent compositions, laundry additive compositions such as fabric enhancer compositions or bleach additive compositions. Preferably, the laundry care composition is a laundry detergent composition. The composition can be a solid, such as a powder, tablet or bar, or a liquid. The composition can be in the form of a unit dose, such as pouch. Suitable unit dose pouches include single compartment and multi-compartment pouches.

  本发明涉及包含羧酸盐染料的洗涤护理组合物。洗涤护理组合物可以是洗涤剂组合物，洗涤添加剂组合物，如织物增良剂组合物或漂白剂添加剂组合物。最好，洗涤护理组合物是洗涤剂组合物。该组合物可以是固体，如粉末、片剂或条形，也可以是液体。该组合物可以是单剂形式，如袋装。适用的单剂袋包括单隔室和多隔室袋。
• [EN] PHTHALAZINONE DERIVATIVES<br/>[FR] DERIVES DE PHTHALAZINONE
  申请人：KUDOS PHARM LTD

  公开号：WO2003093261A1

  公开（公告）日：2003-11-13

  A compound of formula (I); or an isomer, salt, solvate, chemically protected form, or prodrug thereof, wherein A and B together represent an optionally substituted, fused aromatic ring; RL is a C5-7 aryl group substituted in the meta position by the group R2, and optionally further substituted; wherein R2 is selected from formula (II) and formula (III); and its use as a pharmaceutical, in particular for the treatment of diseases ameliorated by inhibiting the activity of PARP.

  一种具有化学式（I）的化合物；或其异构体、盐、溶剂合物、化学保护形式、或前药，其中A和B共同代表一个可选择取代的融合芳香环；RL是一个C5-7芳基基团，在邻位由基团R2取代，并可选择进一步取代；其中R2选自化学式（II）和化学式（III）；以及其作为药物的用途，特别用于治疗通过抑制PARP活性改善的疾病。
• [EN] LAUNDRY CARE COMPOSITION COMPRISING CARBOXYLATE DYE<br/>[FR] COMPOSITION D'ENTRETIEN DU LINGE COMPRENANT UN COLORANT CARBOXYLATE
  申请人：PROCTER & GAMBLE

  公开号：WO2015041814A1

  公开（公告）日：2015-03-26

  The present invention relates to a laundry care composition comprising from 0.00001 wt% to 0.5 wt% thiophene azo carboxylate dye having the structure of Formula I: (Formula I), wherein D1 is a thiophene group; wherein D2 is a carbocylic phenylene; wherein the two N atoms shown in Formula I bound directly to the carbocyclic phenylene are in a para-substitution to one another; wherein R1 is independently selected from [(CH2CR'HO)x(CH2CR"HO)y((CH2)wNH)zQ], C1-12 alkyl, C6-10 aryl, or C7-C22 aryl alkyl; wherein R2 is [(CH2CR'HO)x'(CH2CR"HO)y'((CH2)w'NH)z'Q]; wherein the sum of x + y + x' + y' is in the range of from 0 to 50; wherein x is an integer from 0 to 50; wherein x' is an integer from 0 to 50; wherein y is an integer from 0 to 50; wherein y' is an integer from 0 to 50; wherein w and w' are integers independently selected from 2 and 3; wherein z and z' are integers independently selected from 0 and 1; wherein R' and R" are each independently selected from the group consisting of H, C1-C4 alkyl, CH2O(CH2CH2O)a((CH2)bNH)dQ, phenyl and CH2OR5; wherein each R5 is independently selected from the group consisting of C1-C16 linear or branched alkyl, C6-C14 aryl, and C7-C16 arylalkyl; wherein each a is an integer independently selected from 0 to 2; wherein each b is an integer independently selected from 2 to 3; wherein each d is an integer independently selected from 0 to 1; wherein each Q is independently selected from the group consisting of H and Y, preferably all Q groups are independently selected Y groups; wherein each Y is an independently selected organic radical represented by Formula II (Formula II), wherein independently for each Y group: M is H or a charge balancing cation; m is an integer selected from 0 to 5, preferably 0, 1, 2 or 3, more preferably 0 or 1; n is an integer selected from 0 to 5, preferably 0, 1, 2 or 3, more preferably 0 or 1; the sum of m + n is in the range of from 1 to 10, preferably 1, 2 or 3, more preferably 1 or 2; and each R8 is independently selected from the group consisting of H, C3-18 or C4-C18 linear or branched alkyl, and C3-18 or C4-C18 linear or branched alkenyl; at least one R8 group is not H; wherein the sum of z + z' + d is at least 1; characterized in that the dye comprises at least one Q group that is Y and is either: (a) bound to a N atom in an R1 group wherein the index z is 1; or (b) bound to a N atom in an R2 group wherein the index z' is 1; or (c) bound to a N atom in an R' or R" group wherein the index d is 1.

  本发明涉及一种洗涤护理组合物，其中含有从0.00001重量％到0.5重量％的噻吩偶氮羧酸酯染料，其具有以下结构的公式I：（公式I），其中D1是一个噻吩基团；其中D2是一个碳环苯基；在公式I中所示的两个N原子直接与碳环苯基结合，彼此之间处于对位取代；其中R1独立地选自[(CH2CR'HO)x(CH2CR"HO)y((CH2)wNH)zQ]、C1-12烷基、C6-10芳基或C7-C22芳基烷基；其中R2是[(CH2CR'HO)x'(CH2CR"HO)y'((CH2)w'NH)z'Q]；其中x + y + x' + y'的总和在0至50的范围内；其中x是从0到50的整数；其中x'是从0到50的整数；其中y是从0到50的整数；其中y'是从0到50的整数；其中w和w'是独立选择的整数，取自2和3；其中z和z'是独立选择的整数，取自0和1；其中R'和R"各自独立地选自H、C1-C4烷基、CH2O(CH2CH2O)a((CH2)bNH)dQ、苯基和CH2OR5的群；其中每个R5独立地选自C1-C16直链或支链烷基、C6-C14芳基和C7-C16芳基烷基的群；其中每个a是独立选择的整数，取自0到2；其中每个b是独立选择的整数，取自2到3；其中每个d是独立选择的整数，取自0到1；其中每个Q是独立选择的，取自H和Y的群，最好所有Q群都是独立选择的Y群；其中每个Y是由公式II代表的独立选择的有机基团（公式II），对于每个Y群：M是H或一个电荷平衡阳离子；m是从0到5中选择的整数，最好为0、1、2或3，更好地为0或1；n是从0到5中选择的整数，最好为0、1、2或3，更好地为0或1；m + n的总和在1到10的范围内，最好为1、2或3，更好地为1或2；每个R8独立地选自H、C3-18或C4-C18直链或支链烷基，以及C3-18或C4-C18直链或支链烯基；至少一个R8群不是H；其中z + z' + d的总和至少为1；其特征在于染料包含至少一个Q群，该Q群是Y并且是以下情况之一：（a）与R1群中的N原子结合，其中指数z为1；或（b）与R2群中的N原子结合，其中指数z'为1；或（c）与R'或R"群中的N原子结合，其中指数d为1。
• IMIDE-LINKED MALEIMIDE AND POLYMALEIMIDE COMPOUNDS
  申请人：Mizori Farhad G.

  公开号：US20110130485A1

  公开（公告）日：2011-06-02

  The invention is directed to maleimide thermosets incorporating imide-extended mono-, bis-, or polymaleimide compounds. These imide-extended maleimide compounds are prepared by the condensation of appropriate anhydrides with appropriate diamines to give amine terminated compounds. These compounds are then condensed with excess maleic anhydride to yield imide-extended maleimide compounds.

  这项发明涉及将咪唑烯烃热固性树脂与亚酰亚胺扩展的单、双或多咪唑烯烃化合物结合。这些亚酰亚胺扩展的咪唑烯烃化合物是通过适当的酐与适当的二胺进行缩合反应制备的，以得到末端带有胺基的化合物。然后，这些化合物与过量的马来酸酐缩合，得到亚酰亚胺扩展的咪唑烯烃化合物。
• Solubilization and Targeted Delivery of Drugs With Self-Assembling Amphiphilic Polymers
  申请人：Diwan Anil

  公开号：US20100260743A1

  公开（公告）日：2010-10-14

  There are provided amphiphilic biodegradable copolymers comprising a hydrophilic backbone with pendant aliphatic groups as the hydrophobic component. The polymers form nanoscale molecular aggregates in aqueous environments, which have hydrophobic interiors that are capable of solubilizing insoluble organic compounds such as drugs, vitamins, dyes, and imaging agents. The polymers optionally feature reactive functional groups that provide attachment points for antibodies, ligands, and other targeting moieties useful for the targeted delivery of drugs and imaging agents.

  提供的两性可降解共聚物包括具有羟基亲水骨架和作为疏水组分的脂肪族侧链的共聚物。这些聚合物在水性环境中形成纳米级分子聚集体，具有疏水内部，能够溶解不溶于水的有机化合物，如药物、维生素、染料和成像剂。这些聚合物可选择性地具有反应性功能基团，提供与抗体、配体和其他靶向基团的结合点，有助于药物和成像剂的靶向传递。

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