Bis[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl] oxalate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Bis[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl] oxalate
• 英文别名: bis[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl] oxalate
• 化学式: C₂₀H₃₈O₁₂
• 分子量: 470.5
• InChiKey: NSZFSXOBAOXIRM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  32
• 可旋转键数：
  27
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  126
• 氢给体数：
  0
• 氢受体数：
  12

文献信息

• COMPOSITIONS AND METHODS FOR USE OF CANNABINOIDS FOR NEUROPROTECTION
  申请人：Inmed Pharmaceuticals Inc.

  公开号：EP3958856A1

  公开（公告）日：2022-03-02
• [EN] COMPOSITIONS AND METHODS FOR USE OF CANNABINOIDS FOR NEUROPROTECTION<br/>[FR] COMPOSITIONS ET MÉTHODES D'UTILISATION DE CANNABINOÏDES POUR LA NEUROPROTECTION
  申请人：INMED PHARMACEUTICALS INC

  公开号：WO2020215164A1

  公开（公告）日：2020-10-29

  Provided herein are methods and compositions for neuroprotection. The neuroprotective composition can be or include cannabinol or a derivative thereof. The neuroprotective composition can be used in the treatment of a neurodegenerative disease. The neuroprotective composition can be used to protect retinal neurons from degeneration in a subject in need thereof, such as for treatment of glaucoma.
• [EN] COMPOSITIONS AND METHODS FOR TREATING NEURONAL DISORDERS WITH CANNABINOIDS<br/>[FR] COMPOSITIONS ET PROCÉDÉS DE TRAITEMENT DES TROUBLES NEURONAUX À L'AIDE DE CANNABINOÏDES
  申请人：[en]INMED PHARMACEUTICALS INC.

  公开号：WO2022082313A1

  公开（公告）日：2022-04-28

  Provided herein are methods and compositions comprising a cannabinoid compound for providing neuroprotection and/or stimulating neuritogenesis. The cannabinoid compound can be a compound of Formula (I), wherein R1is COOH or H, R2is C3H7or C5H11, R3is H or Me, R4and R5are Me or (CH2)2CH=C(CH3)2, such as CBGA, a derivative thereof, a prodrug thereof, or combinations thereof, and can be used in the treatment of neurodegenerative diseases, or to promote neurite elongation and/or restore neurite formation in patients in need thereof.