2-methyl-1H-thieno[3,4-b]pyrrole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 2-methyl-1H-thieno[3,4-b]pyrrole
• 化学式: C₇H₇NS
• 分子量: 137.2
• InChiKey: CCIRPBXSLAIJNV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  44
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• MODULATORS OF OPIOID RECEPTORS AND METHODS OF USE THEREOF
  申请人：Sunovion Pharmaceuticats Inc.

  公开号：US20140288050A1

  公开（公告）日：2014-09-25

  Provided herein are compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as pain, neurological disorders, psychiatric disorders, and neuromuscular disorders. Compounds provided herein modulate the activity of opioid receptor (e.g., μ-opioid receptor) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.