17,18-Dihydroxy-17-(1-hydroxy-2-oxopentadecyl)tetratriacontane-16,19-dione

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 17,18-Dihydroxy-17-(1-hydroxy-2-oxopentadecyl)tetratriacontane-16,19-dione
• 化学式: C₄₉H₉₄O₆
• 分子量: 779.3
• InChiKey: QIJDPTBCXYSTEG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  18.3
• 重原子数：
  55
• 可旋转键数：
  45
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  112
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• Functional associative coatings for nanoparticles
  申请人：Hainfeld James F.

  公开号：US20080089836A1

  公开（公告）日：2008-04-17

  Described herein are nanoparticles that are coated with a bilayer of molecules formed from surface binding molecules and amphiphatic molecules. The bilayer coating self assembles on the nanoparticles from readily available materials/molecules. The modular design of the bilayer coated nanoparticles provides a means for readily and efficiently optimizing the properties of the bilayer coated nanoparticle compositions. Also described herein are uses of such nanoparticles in medicine, laboratory techniques, industrial and commerical applications.

  本文描述了一种纳米颗粒，其表面涂覆有由表面结合分子和两亲分子形成的双层分子层。该双层涂层可以自组装在纳米颗粒上，使用易得的材料/分子。双层涂层纳米颗粒的模块化设计提供了一种方便和高效地优化其性质的方法。此外，本文还描述了这种纳米颗粒在医学、实验室技术、工业和商业应用中的用途。
• Probe compound for detecting and isolating enzymes and means and methods using the same
  申请人：Helmholtz-Zentrum für Infektionsforschung GmbH

  公开号：EP2230312A1

  公开（公告）日：2010-09-22

  The present invention relates to a probe compound that can comprise any substrate or metabolite of an enzymatic reaction in addition to an indicator component, such as, for example, a fluorescence dye, or the like. Moreover, the present invention relates to means for detecting enzymes in form of an array, which comprises any number of probe compounds of the invention which each comprise a different metabolite of interconnected metabolites representing the central pathways in all forms of life. Moreover, the present invention relates to a method for detecting enzymes involving the application of cell extracts or the like to the array of the invention which leads to reproducible enzymatic reactions with the substrates. These specific enzymatic reactions trigger the indicator (e.g. a fluorescence signal) and bind the enzymes to the respective cognate substrates. Moreover, the invention relates to means for isolating enzymes in form of nanoparticles coated with the probe compound of the invention. The immobilisation of the cognate substrates or metabolites on the surface of nanoparticles by means of the probe compounds allows capturing and isolating the respective enzyme, e.g. for subsequent sequencing.

  本发明涉及一种探针化合物，它可以包括酶反应的任何底物或代谢物，此外还包括指示成分，例如荧光染料或类似物。此外，本发明还涉及以阵列形式检测酶的方法，该阵列由任意数量的本发明探针化合物组成，每种探针化合物由代表所有生命形式中中心途径的相互关联的代谢物中的不同代谢物组成。此外，本发明还涉及一种检测酶的方法，该方法涉及将细胞提取物或类似物应用于本发明的阵列，从而导致与底物发生可重复的酶反应。这些特定的酶反应会触发指示剂（如荧光信号），并将酶与各自的同源底物结合。此外，本发明还涉及以涂覆有本发明探针化合物的纳米颗粒形式分离酶的方法。通过探针化合物将同源底物或代谢物固定在纳米颗粒表面，可以捕获和分离相应的酶，例如用于后续测序。
• Composition and method for early bloom thinning of fruit trees and controlling cracking of fruits
  申请人：——

  公开号：US20010039246A1

  公开（公告）日：2001-11-08

  A composition and method for early bloom thinning of fruit trees and controlling cracking, wherein the composition provides that glyceride type of lipids are effective compounds for bloom thinning of fruit trees and controlling cracking of fruits and the method comprises making an aqueous emulsion with these lipids as active ingredients and spraying the emulsion on fruit trees at appropriate phenophases for blossom thinning or fruit cracking control. The composition further provides that copper compounds act as blossom thinning agents but cause phytotoxicity to trees and a mixture of the said lipid emulsion and copper compounds displays higher thinning effect than each applied alone and does not cause phytotoxicity to trees.

  一种用于果树早期疏花和控制裂果的组合物和方法，其中该组合物提供了甘油酯类脂质是果树疏花和控制果实裂果的有效化合物，该方法包括以这些脂质为有效成分制成水乳剂，并在适当的物候期将该乳剂喷洒在果树上，以达到疏花或控制果实裂果的目的。该组合物还规定，铜化合物可作为疏花剂，但会对树木造成植物毒性，而上述脂质乳液和铜化合物的混合物比单独使用每种化合物具有更高的疏花效果，且不会对树木造成植物毒性。
• US7906147B2
  申请人：——

  公开号：US7906147B2

  公开（公告）日：2011-03-15