Hex-3-enyl undec-10-enoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Hex-3-enyl undec-10-enoate
• 化学式: C₁₇H₃₀O₂
• 分子量: 266.4
• InChiKey: XCVDCWGZWKLBOB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METATHESIS CATALYSTS<br/>[FR] RÉACTIONS DE DÉRIVÉS OLÉFINIQUES EN PRÉSENCE DE CATALYSEURS DE MÉTATHÈSE
  申请人：UMICORE AG & CO KG

  公开号：WO2019158485A1

  公开（公告）日：2019-08-22

  The invention provides a method for synthesizing musk macrocycles comprising contacting an easily accessible diene starting materials bearing a Z-olefin moiety and performing a ring closing metathesis reaction in the presence of a Group 8 olefin metathesis catalyst.

  本发明提供了一种合成麝香大环的方法，包括将带有Z-烯烃基团的易得到的二烯起始材料接触，并在第8族烯烃交换催化剂的存在下进行环闭合交换反应。
• Reactions of olefin derivatives in the presence of methathesis catalysts
  申请人：Umicore AG & Co. KG

  公开号：US11161104B2

  公开（公告）日：2021-11-02

  The invention provides a method for synthesizing musk macrocycles comprising contacting an easily accessible diene starting materials bearing a Z-olefin moiety and performing a ring closing metathesis reaction in the presence of a Group 8 olefin metathesis catalyst.

  本发明提供了一种合成麝香大环的方法，包括接触含有 Z-烯烃分子的易获得二烯起始材料，并在第 8 族烯烃偏聚催化剂存在下进行闭环偏聚反应。
• Using stereoretention for the stereoselective formation of e-macrocycles with Ru-based olefin metathesis catalysts
  申请人：California Institute of Technology

  公开号：US11407726B2

  公开（公告）日：2022-08-09

  This invention relates generally to the synthesis of E-macrocycles using stereoretentive ruthenium olefin metathesis catalysts supported by dithioiate ligands. Macrocycles were generated with excellent selectivity (>99% E) and in moderate to high/good yields (47% to 80% yield; 58% to 80% yield) from diene starting materials bearing two E-olefins or bearing one E-olefin and one terminal olefin, A variety of rings were constructed, ranging from 12- to 18-membered macrocycles, including the antibiotic recifeiolide. The invention has utility in the fields of organometallics and organic synthesis.

  本发明一般涉及使用二硫代配体支持的立体结构钌烯烃偏析催化剂合成 E-大环。从含有两个 E-烯烃或含有一个 E-烯烃和一个末端烯烃的二烯起始材料生成的大环具有极佳的选择性（>99% E）和中等至高/良好的收率（收率为 47% 至 80%；收率为 58% 至 80%）。本发明可用于有机金属和有机合成领域。
• EP3752494A1
  申请人：——

  公开号：EP3752494A1

  公开（公告）日：2020-12-23
• USING STEREORETENTION FOR THE STEREOSELECTIVE FORMATION OF E-MACROCYCLES WITH RU-BASED OLEFIN METATHESIS CATALYSTS
  申请人：California Institute of Technology

  公开号：US20200385360A1

  公开（公告）日：2020-12-10

  This invention relates generally to the synthesis of E-macrocycles using stereoretentive ruthenium olefin metathesis catalysts supported by dithioiate ligands. Macrocycles were generated with excellent selectivity (>99% E) and in moderate to high/good yields (47% to 80% yield; 58% to 80% yield) from diene starting materials bearing two E-olefins or bearing one E-olefin and one terminal olefin, A variety of rings were constructed, ranging from 12- to 18-membered macrocycles, including the antibiotic recifeiolide. The invention has utility in the fields of organometallics and organic synthesis.