(S)-2-amino-5-bromo-pentanoic acid hydrochloride | 1206813-73-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (S)-2-amino-5-bromo-pentanoic acid hydrochloride
• 英文别名: (2S)-2-amino-5-bromopentanoic acid;hydrochloride
• CAS: 1206813-73-1
• 化学式: C₅H₁₀BrNO₂*ClH
• 分子量: 232.505
• InChiKey: CLVMTCIQIDCRQB-WCCKRBBISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.0
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  63.3
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  methyl (2S)-2-[bis(tert-butoxycarbonyl)amino]-5-bromopentanoate 在 盐酸 、 水 作用下， 反应 24.0h， 以98%的产率得到(S)-2-amino-5-bromo-pentanoic acid hydrochloride
  参考文献：
  名称：

  OPTICALLY ACTIVE alpha-AMINO ACID INTO WHICH BSH IS INTRODUCED AND METHOD FOR SYNTHESIZING THE SAME

  摘要：

  公开号：

  EP2319850B1

文献信息

• OPTICALLY ACTIVE ALPHA-AMINO ACID INTO WHICH BSH IS INTRODUCED AND METHOD FOR SYNTHESIZING THE SAME
  申请人：Kirihata Mitsunori

  公开号：US20110124914A1

  公开（公告）日：2011-05-26

  Disclosed is the method for producing an optically active BSH amino acid, which comprises a step of reacting an optically active a-amino acid derivative having a halogen in a side chain with a cyanoethyl BSH compound represented by formula (1). An optically active BSH amino acid obtained by the method is also disclosed.

  本发明揭示了一种生产光学活性BSH氨基酸的方法，其中包括将侧链中带有卤素的光学活性a-氨基酸衍生物与由式（1）表示的氰乙基BSH化合物反应的步骤。本发明还揭示了通过该方法获得的光学活性BSH氨基酸。
• Optically active α-amino acid into which BSH is introduced and method for synthesizing the same
  申请人：Kirihata Mitsunori

  公开号：US08431738B2

  公开（公告）日：2013-04-30

  Disclosed is the method for producing an optically active BSH amino acid, which comprises a step of reacting an optically active a-amino acid derivative having a halogen in a side chain with a cyanoethyl BSH compound represented by formula (1). An optically active BSH amino acid obtained by the method is also disclosed.

  本发明公开了一种制备光学活性BSH氨基酸的方法，包括以下步骤：将具有侧链中卤素的光学活性α-氨基酸衍生物与由式（1）表示的氰乙基BSH化合物反应。本发明还公开了通过该方法获得的光学活性BSH氨基酸。
• OPTICALLY ACTIVE -AMINO ACID INTO WHICH BSH IS INTRODUCED AND METHOD FOR SYNTHESIZING THE SAME
  申请人：Stella Pharma Corporation

  公开号：EP2319850A1

  公开（公告）日：2011-05-11

  Disclosed is the method for producing an optically active BSH amino acid, which comprises a step of reacting an optically active α-amino acid derivative having a halogen in a side chain with a cyanoethyl BSH compound represented by formula (1). An optically active BSH amino acid obtained by the method is also disclosed.

  本发明公开了生产光学活性 BSH 氨基酸的方法，该方法包括使侧链中含有卤素的光学活性 α-氨基酸衍生物与由式（1）代表的氰乙基 BSH 化合物反应的步骤。还公开了通过该方法获得的光学活性 BSH 氨基酸。
• US8431738B2
  申请人：——

  公开号：US8431738B2

  公开（公告）日：2013-04-30
• OPTICALLY ACTIVE alpha-AMINO ACID INTO WHICH BSH IS INTRODUCED AND METHOD FOR SYNTHESIZING THE SAME
  申请人：Stella Pharma Corporation

  公开号：EP2319850B1

  公开（公告）日：2017-03-29