Asp-His | 22677-56-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Asp-His
• 英文别名: (3S)-3-amino-4-[[(1S)-1-carboxy-2-(1H-imidazol-5-yl)ethyl]amino]-4-oxobutanoic acid
• CAS: 22677-56-1
• 化学式: C₁₀H₁₄N₄O₅
• 分子量: 270.245
• InChiKey: HSPSXROIMXIJQW-BQBZGAKWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.4
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  158
• 氢给体数：
  5
• 氢受体数：
  7

文献信息

• EXTERNAL GRADIENT CHROMATOFOCUSING
  申请人：Cryobiophysica, Inc.

  公开号：EP1628729A2

  公开（公告）日：2006-03-01
• External gradient chromatofocusing
  申请人：Tsonev I. Latchezar

  公开号：US20070144973A1

  公开（公告）日：2007-06-28

  The invention provides novel methods for the separation of charged molecules such as proteins according to the isoelectric points (pI's) and includes the systems and buffering compositions employed for isolating charged molecules. The invention further provides for modifications to the above described chromatographic methods that enable the separation of charged molecules exhibiting virtually identical pI's by shifting both the buffer's pKa and the pI's of the eluted charged molecules while they are traversing the ion exchange column.
• US7790025B2
  申请人：——

  公开号：US7790025B2

  公开（公告）日：2010-09-07
• [EN] EXTERNAL GRADIENT CHROMATOFOCUSING<br/>[FR] CHROMATOFOCALISATION A GRADIENT EXTERNE
  申请人：DNAVAX INC

  公开号：WO2004103519A2

  公开（公告）日：2004-12-02

  The invention provides novel methods for the separation of charged molecules such a proteins according to their isoelectric points (pI's) and includes the systems and buffering compositions employed for isolating charged molecules. The invention further provides for modifications to the above described chromatographic methods that enable the separation of charged molecules exhibiting virtually identical pl's by shifting both the buffer's pKa and the pl's of the eluted charged molecules while they are traversing the ion exchange column.