2-Phenyl-1,3-thiazolidine-4-carboxamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Phenyl-1,3-thiazolidine-4-carboxamide
• 化学式: C₁₀H₁₂N₂OS
• 分子量: 208.28
• InChiKey: WGDMOZRYDFNRMJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  80.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• COMPOUNDS FOR THE TREATMENT OF CANCER
  申请人：University of Tennessee Research Foundation

  公开号：EP2303021A2

  公开（公告）日：2011-04-06
• [EN] COMPOUNDS FOR THE TREATMENT OF CANCER<br/>[FR] COMPOSÉS DESTINÉS À TRAITER LE CANCER
  申请人：UNIV TENNESSEE RES FOUNDATION

  公开号：WO2010074776A2

  公开（公告）日：2010-07-01

  Compounds according to formula (I) are disclosed, (I), where Q is S, N, or O; X is optional, and can be O=, S=, =N-NH2, =N-OH, or -OH; Y is optional and can be -N(H)-, O, or C1 to C20 hydrocarbon; and R1 and R2 are each independently substituted or unsubstituted single-, fused- or multiple-ring aryl or (hetero)cyclic ring systems. Methods of making these compounds, pharmaceutical compositions containing the compounds, and their use, particularly for treating or preventing cancer, are also disclosed.