[4-(diaminomethylcarbamoyloxymethyl)-2-methoxyphenyl] 3-[3-[3-[[(2S)-3-amino-2-[[(2S)-2-[[2-[2-[2-[[(2S)-2,6-bis[[2-[2-[2-[[3-oxo-5-(3-sulfanylpropanoylamino)pentyl]amino]ethoxy]ethoxy]acetyl]amino]hexanoyl]amino]ethoxy]ethoxy]acetyl]amino]-8-oxo-9-[2-[2-[[(2S)-2-[[2-[2-[2-[[3-oxo-5-(3-sulfanylpropanoylamino)pentyl]amino]ethoxy]ethoxy]acetyl]amino]-6-[[2-[2-[2-[3-(3-sulfanylpropanoylamino)propanoylamino]ethoxy]ethoxy]acetyl]amino]hexanoyl]amino]ethoxy]ethoxy]nonanoyl]amino]-3-oxopropyl]amino]-3-oxopropyl]-2,4-dioxocyclopentyl]sulfanylpropanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: [4-(diaminomethylcarbamoyloxymethyl)-2-methoxyphenyl] 3-[3-[3-[[(2S)-3-amino-2-[[(2S)-2-[[2-[2-[2-[[(2S)-2,6-bis[[2-[2-[2-[[3-oxo-5-(3-sulfanylpropanoylamino)pentyl]amino]ethoxy]ethoxy]acetyl]amino]hexanoyl]amino]ethoxy]ethoxy]acetyl]amino]-8-oxo-9-[2-[2-[[(2S)-2-[[2-[2-[2-[[3-oxo-5-(3-sulfanylpropanoylamino)pentyl]amino]ethoxy]ethoxy]acetyl]amino]-6-[[2-[2-[2-[3-(3-sulfanylpropanoylamino)propanoylamino]ethoxy]ethoxy]acetyl]amino]hexanoyl]amino]ethoxy]ethoxy]nonanoyl]amino]-3-oxopropyl]amino]-3-oxopropyl]-2,4-dioxocyclopentyl]sulfanylpropanoate
• 化学式: C₁₀₉H₁₈₅N₂₁O₃₈S₅
• 分子量: 2558.1
• InChiKey: KPIVYGHPRHLGBU-YYCFLPOESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -10.3
• 重原子数：
  173
• 可旋转键数：
  117
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  855
• 氢给体数：
  25
• 氢受体数：
  48

文献信息

• Protein-proteophore complexes
  申请人：Vetter Dirk

  公开号：US20070020224A1

  公开（公告）日：2007-01-25

  The application relates to a composition comprising a hyperbranched polymer attached to a core and a biologically active moiety. The biologically active moiety is attached to the core by means of a substantially non-enzymatically cleavable linker L. The composition can be used to deliver the biologically active moiety to its target.