(2R,3S,4S)-2,3,4-tribenzyloxy-hex-5-ene-1-al di-n-propyl dithioacetal | 343934-78-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2R,3S,4S)-2,3,4-tribenzyloxy-hex-5-ene-1-al di-n-propyl dithioacetal
• 英文别名: [(2R,3S,4S)-3,4-bis(phenylmethoxy)-1,1-bis(propylsulfanyl)hex-5-en-2-yl]oxymethylbenzene
• CAS: 343934-78-1
• 化学式: C₃₃H₄₂O₃S₂
• 分子量: 550.827
• InChiKey: PHNXKOPMUZDAQK-OWHBQTKESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.3
• 重原子数：
  38
• 可旋转键数：
  19
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  78.3
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  (2R,3S,4S)-2,3,4-tribenzyloxy-hex-5-ene-1-al di-n-propyl dithioacetal 在 无水碳酸镉 、 mercury dichloride 作用下， 以 水 、 丙酮 为溶剂， 反应 24.0h， 生成 2,3,4-Tri-O-benzyl-5,6-dideoxy-L-arabino-hex-5-enose
  参考文献：
  名称：

  Cycloaddition reactions of carbohydrate derivatives. Part 8: Intramolecular cycloaddition of nitrilimines derived from sugars

  摘要：

  Nitrilimines containing a carbon-carbon double bond were prepared in several steps from 3,3,4-tri-O-benzyl-D-xylose, D-ribose and L-arabinose derivatives and their intramolecular 1,3-dipolar cycloaddition reactions were studied. The results were examined with molecular modelling and compared with the literature data for similar cycloadditions. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(01)00050-7
• 作为产物：
  描述：

  2,3,4-tri-O-benzyl-D-galactose 1,1-di(n-propyl)dithioacetal 在 lead(IV) acetate 、 正丁基锂 作用下， 以 正己烷 、 甲苯 为溶剂， 反应 3.0h， 生成 (2R,3S,4S)-2,3,4-tribenzyloxy-hex-5-ene-1-al di-n-propyl dithioacetal
  参考文献：
  名称：

  Cycloaddition reactions of carbohydrate derivatives. Part 8: Intramolecular cycloaddition of nitrilimines derived from sugars

  摘要：

  Nitrilimines containing a carbon-carbon double bond were prepared in several steps from 3,3,4-tri-O-benzyl-D-xylose, D-ribose and L-arabinose derivatives and their intramolecular 1,3-dipolar cycloaddition reactions were studied. The results were examined with molecular modelling and compared with the literature data for similar cycloadditions. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(01)00050-7