[(1R,2S,4R,5S)-9,9-Dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] 2-hydroxy-2,2-dithiophen-2-ylacetate;bromide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: [(1R,2S,4R,5S)-9,9-Dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] 2-hydroxy-2,2-dithiophen-2-ylacetate;bromide
• 化学式: C19H22BrNO4S2
• 分子量: 472.4
• InChiKey: DQHNAVOVODVIMG-CJTHRXGHSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.65
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  116
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• PREVENTIVE AND/OR REMEDY FOR HAND AND FOOT SYNDROME
  申请人：ONO Pharmaceutical Co., Ltd.

  公开号：EP2554184A1

  公开（公告）日：2013-02-06

  The agent for the prevention and/or treatment of Hand-Foot Syndrome comprising a compound with anticholinergic activity can be provided. The agent for the prevention and/or treatment of Hand-Foot Syndrome comprising a compound with anticholinergic activity can be safely administered to the patients with Hand-Foot Syndrome, and has shown the superior preventive and/or treatment effect against Hand-Foot Syndrome.

  可以提供由具有抗胆碱能活性的化合物组成的预防和/或治疗手足综合征的制剂。由具有抗胆碱能活性的化合物组成的预防和/或治疗手足综合征的制剂可安全地用于手足综合征患者，并显示出对手足综合征具有卓越的预防和/或治疗效果。
• PREVENTIVE AND/OR THERAPEUTIC AGENT OF HAND-FOOT SYNDROME
  申请人：Ishizaka Kazuhiro

  公开号：US20130045956A1

  公开（公告）日：2013-02-21

  The agent for the prevention and/or treatment of Hand-Foot Syndrome comprising a compound with anticholinergic activity can be provided. The agent for the prevention and/or treatment of Hand-Foot Syndrome comprising a compound with anticholinergic activity can be safely administered to the patients with Hand-Foot Syndrome, and has shown the superior preventive and/or treatment effect against Hand-Foot Syndrome.
• US8729056B2
  申请人：——

  公开号：US8729056B2

  公开（公告）日：2014-05-20