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3-Phenacetyl-benzothiophen | 4565-11-1

中文名称
——
中文别名
——
英文名称
3-Phenacetyl-benzothiophen
英文别名
1-benzo[b]thiophen-3-yl-2-phenyl-ethanone;1-Benzo[b]thiophen-3-yl-2-phenyl-aethanon;1-(Benzo[b]thiophen-3-yl)-2-phenylethanone;1-(1-benzothiophen-3-yl)-2-phenylethanone
3-Phenacetyl-benzo<b>thiophen化学式
CAS
4565-11-1
化学式
C16H12OS
mdl
——
分子量
252.337
InChiKey
ZRBKQGPAFXOPNN-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    4.4
  • 重原子数:
    18
  • 可旋转键数:
    3
  • 环数:
    3.0
  • sp3杂化的碳原子比例:
    0.06
  • 拓扑面积:
    45.3
  • 氢给体数:
    0
  • 氢受体数:
    2

上下游信息

  • 下游产品
    中文名称 英文名称 CAS号 化学式 分子量

反应信息

  • 作为反应物:
    描述:
    3-Phenacetyl-benzothiophen 在 palladium on activated charcoal 、 乙醇双氧水乙酸酐一水合肼溶剂黄146二乙二醇 作用下, 生成 3-phenethyl-2,3-dihydro-benzo[b]thiophene-1,1-dioxide
    参考文献:
    名称:
    The Internal Condensation of 2,4-Diphenyl-1-butanesulfonyl Chloride to a Five- in Preference to a Seven-membered Cyclic Sulfone1
    摘要:
    DOI:
    10.1021/ja01110a020
  • 作为产物:
    描述:
    苯并噻吩 以63%的产率得到
    参考文献:
    名称:
    USMANOV R.; HYMAHOB I. U.; NASYROV I. M., DOKL. AKAD. FANXOI PCC TOCHIKISTON, DOKL. AN TADZHSSR , 1975, 18+
    摘要:
    DOI:
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文献信息

  • VIRAL REPLICATION INHIBITORS
    申请人:KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D
    公开号:US20140213586A1
    公开(公告)日:2014-07-31
    The present invention relates to a series of novel compounds, methods to prevent or treat viral infections in animals by using the novel compounds and to said novel compounds for use as a medicine, more preferably for use as a medicine to treat or prevent viral infections, particularly infections with RNA viruses, more particularly infections with viruses belonging to the family of the Flaviviridae, and yet more particularly infections with the Dengue virus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the novel compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of viral infections. The invention also relates to processes for preparation of the compounds.
    本发明涉及一系列新化合物,使用这些新化合物预防或治疗动物的病毒感染的方法,以及这些新化合物的药物用途,更好地用于治疗或预防病毒感染,特别是RNA病毒感染,更特别是属于黄病毒科的病毒感染,更进一步地是登革热病毒感染。本发明还涉及新化合物的药物组成物或复合制剂,以及用于预防或治疗病毒感染的药物组成物或制剂。本发明还涉及化合物的制备方法。
  • Viral replication inhibitors
    申请人:KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. Leuven R&D
    公开号:US10550123B2
    公开(公告)日:2020-02-04
    The present invention relates to a series of novel compounds, methods to prevent or treat viral infections in animals by using the novel compounds and to said novel compounds for use as a medicine, more preferably for use as a medicine to treat or prevent viral infections, particularly infections with RNA viruses, more particularly infections with viruses belonging to the family of the Flaviviridae, and yet more particularly infections with the Dengue virus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the novel compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of viral infections. The invention also relates to processes for preparation of the compounds.
    本发明涉及一系列新型化合物、使用这些新型化合物预防或治疗动物病毒感染的方法以及用作药物的所述新型化合物,更优选用作治疗或预防病毒感染的药物,特别是 RNA 病毒感染,更特别是属于黄病毒科的病毒感染,更特别是登革热病毒感染。本发明还涉及新型化合物的药物组合物或组合制剂、用作药物的组合物或制剂,更优选用于预防或治疗病毒感染。本发明还涉及化合物的制备工艺。
  • 609. The chemistry of carcinogenic nitrogen-compounds. Part III. Polysubstituted pyrroles and indoles as potential cocarcinogens
    作者:Ng.Ph. Buu-Hoï
    DOI:10.1039/jr9490002882
    日期:——
  • Buu-Hoi; Cagniant, Recueil des Travaux Chimiques des Pays-Bas, 1948, vol. 67, p. 64,70
    作者:Buu-Hoi、Cagniant
    DOI:——
    日期:——
  • 1159. Synthesis of methyl derivatives of naphtho[2,1-b]thiophen and 11-thiabenzo[a]fluorene by photocyclisation of stilbene isosters
    作者:W. Carruthers、H. N. M. Stewart
    DOI:10.1039/jr9650006221
    日期:——
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