methacrylic acid-β-diethylaminoethylamide | 13173-42-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: methacrylic acid-β-diethylaminoethylamide
• 英文别名: 2-[N,N-diethylamino] ethyl[meth-]acrylamide；N-diethylaminoethyl (meth)acrylamide；NoName_3510；N-[2-(diethylamino)ethyl]-2-methylprop-2-enamide
• CAS: 13173-42-7
• 化学式: C₁₀H₂₀N₂O
• 分子量: 184.282
• InChiKey: GVBMMNAPRZDGEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  哌啶 、 methacrylic acid-β-diethylaminoethylamide 以 水 为溶剂， 生成 N-(2-Diethylamino-ethyl)-2-methyl-3-piperidin-1-yl-propionamide
  参考文献：
  名称：

  Shirshin; Kazakov; Kazantsev, Russian Journal of General Chemistry, 1998, vol. 68, # 8, p. 1261 - 1263

  摘要：

  DOI：

文献信息

• Innervated artificial tissues and uses thereof
  申请人：Griffith May

  公开号：US20060034807A1

  公开（公告）日：2006-02-16

  A three dimensional, innervated artificial tissue comprising a bio-synthetic matrix is provided. The artificial tissue supports cell growth, including surface coverage and three-dimensional cell in-growth, as well as nerve in-growth. Methods of preparing the innervated artificial tissue and methods of innervating artificial tissues or tissue substitutes are also provided. The artificial tissue is useful for in vitro testing of various pharmaceutical, cosmetic and household products.

  提供了一种包括生物合成基质的三维神经化人工组织。这种人工组织支持细胞生长，包括表面覆盖和三维细胞生长，以及神经生长。还提供了制备这种神经化人工组织的方法，以及神经化人工组织或组织替代品的方法。这种人工组织对于体外测试各种药物、化妆品和家用产品非常有用。
• Bio-synthetic matrix and uses thereof
  申请人：Griffith May

  公开号：US20060134050A1

  公开（公告）日：2006-06-22

  A bio-synthetic matrix comprising a hydrogel which is formed by cross-linking a synthetic polymer and a bio-polymer is provided. The matrix is robust, biocompatible and non-cytotoxic and is capable of supporting cell in-growth in vivo. The matrix can be tailored to further comprise one or more bioactive agents. The matrix may also comprise cells encapsulated and dispersed therein, which are capable of proliferating upon deposition of the matrix in vivo. Methods of preparing the bio-synthetic matrix and the use of the matrix in vivo for tissue engineering or drug delivery applications are also provided.

  提供一种生物合成基质，包括通过交联合成聚合物和生物聚合物形成的水凝胶。该基质坚固、生物相容且无细胞毒性，能够在体内支持细胞生长。该基质可以定制以进一步包含一个或多个生物活性剂。该基质还可以包含封装和分散其中的细胞，这些细胞能够在体内沉积基质后增殖。还提供了制备生物合成基质的方法以及在体内用于组织工程或药物传递应用的基质的使用。
• COPOLYMERS AND COMPOSITIONS WITH ANTI-ADHESIVE AND ANTIMICROBIAL PROPERTIES
  申请人：BASF SE

  公开号：US20160235062A1

  公开（公告）日：2016-08-18

  The invention relates to a copolymer exhibiting both antimicrobial and anti-adhesive properties as well as to a hydrogel. Said hydrogel is obtained from the inventive copolymer and a substrate. Another part of the invention is a process for making the hydrogel, as well as different uses of the inventive copolymer as well as of the hydrogel.

  该发明涉及一种既具有抗菌和抗粘附性能的共聚物，又涉及一种水凝胶。所述水凝胶是由该创新共聚物和基质制得的。该发明的另一部分是制备水凝胶的方法，以及该创新共聚物和水凝胶的不同用途。
• Polymer and photoresist compositions
  申请人：Shipley Company, L.L.C.

  公开号：US20020173680A1

  公开（公告）日：2002-11-21

  Disclosed are spirocyclic olefin polymers, methods of preparing spirocyclic olefin polymers, photoresist compositions including spirocyclic olefin resin binders and methods of forming relief images using such photoresist compositions.

  本文披露了螺环烯烃聚合物、制备螺环烯烃聚合物的方法、包括螺环烯烃树脂粘合剂的光刻胶组合物，以及利用这种光刻胶组合物形成凸版图像的方法。
• Reactive monomer composition modified by a small-amount of lactones, an acrylic polyol resin, a curable resin composition, and a coating composition
  申请人：——

  公开号：US20040171867A1

  公开（公告）日：2004-09-02

  The present invention Nos. I and II relate to a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones in which a proportion of monomers having two or more continuous chains (n≧2) of lactone is less than 50% (area % by GPC) which is obtained by a ring-opening polymerization of a lactone with a hydroxyalkyl(meth)acrylate, a method for the preparation thereof, and an acrylic polyol resin using thereof, 1 (in the formula, R, R 1 , R 2 , and R 3 are independently a hydrogen or a methyl group, “j” is an integer of 2-6, xn pieces of R 4 and R 5 are independently a hydrogen atom or an alkyl group having a carbon number of 1-12, “x” is 4-7, “n” is 0 or an integer of not less than 1, and an average value of “n” in the composition is not less than 0.3 to less than 1.0). By allowing to react the composition with other ethylenic unsaturated monomer and to formulate with a commonly-used crosslinking agent and other commonly-used components, there can be obtained a well-balanced high quality finishing agent for industries, an ultraviolet ray- or electron beam-curable coating agent, a composition which can be modified for a reactive improver, etc., and an acrylic polyol resin using thereof. The present invention No. III relates to a curable resin composition containing 0.5-80 parts by weight of an acrylic polyol resin (A) obtained using a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones and 0.5-50 parts by weight of a melamine resin (B) [total of the (A) and (B) does not exceed, 100 parts by weight] as essential components. By the composition, even in a melamine-based curing system which is low in price, there can be obtained a curable-type coating composition in which an acid resistance is improved and highly well-balanced between an acid resistance and abrasion resistance, and which is also excellent in flexural resistance and adhesion in recoating. The present invention No. IV relates to a curable resin composition containing 0.5-80 parts by weight of an acrylic polyol resin (A) containing a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones as a polymerizing component and 0.5-50 parts by weight of a melamine resin (B) [total of the (A) and (B) does not exceed 100 parts by weight] as essential components. By the composition, even in a melamine-based curing system which is low in price, there can be obtained a curable-type coating composition in which an acid resistance is improved and highly well-balanced between an acid resistance and abrasion resistance. The present invention No. V relates to a curable resin composition containing 0.5-80 parts by weight of an acrylic polyol resin (A) obtained using a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones and 0.5-50 parts by weight of a polyisocyanate compound (B) [total of the (A) and (B) does not exceed 100 parts by weight] as essential components. By the composition, even in an isocyanate-based curing system, there can be obtained a curable-type coating composition in which a pot life is long and workability is improved, and which is highly well-balanced between an acid resistance and abrasion resistance, and which can provide a coating layer which is excellent also in flexural resistance and adhesion in recoating. The present invention No. VI relates to a curable resin composition containing 0.5-80 parts by weight of an acrylic polyol resin (A) obtained using a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones and 0.5-50 parts by weight of a polyisocyanate compound (B) [total of the (A) and (B) does not exceed 100 parts by weight] as essential components. By the composition, even in an isocyanate-based curing system, there can be obtained a curable-type coating composition in which a pot life is long and workability is improved, and which is highly well-balanced between an acid resistance and abrasion resistance, and which can provide a coating layer which is excellent also in flexural resistance and adhesion in recoating. The present invention No. VII relates to a thermosetting resin composition containing 2-50 parts of an acrylic polyol resin obtained using a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones and 30-80 parts of an acrylic copolymer having an alkoxysilyl group. By the composition, there can be obtained a thermosetting resin composition in which crosslinking density is elevated and hardness and abrasion resistance are improved as well as solving a problem of acid resistance and odor. The present invention No. VIII relates to a carboxylic group-contained acrylate composition (a′) modified by a small amount of lactones represented by a formula described below by allowing to react a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones with a carboxylic anhydride, 2 (in the formula, R, R 1 , R 2 , and R 3 are independently a hydrogen or a methyl group, “j” is an integer of 2-6, xn pieces of R 4 and R 5 are independently a hydrogen atom or an alkyl group having a carbon number of 1-12, “x” is 4-7 , “n” is 0 or an integer of not less than 1, an average value of “n” in the composition is not less than 0.3 to less than 1.0 , R 6 is a residual group of a carboxylic acid, and “m” is an integer of 1-3), and relates to a method for the preparation thereof. By the method, there can be readily, efficiently, and economically obtained the carboxylic group-contained acrylate monomer composition modified by a small amount of lactones. The present invention No. IX relates to a curable resin composition containing 10-70 parts of an acrylic polycarboxylic resin essentially containing the carboxylic group-contained hydroxy(meth)acrylate monomer composition (a′) modified by a small amount of lactones as a polymerizing component and 0.5-80 parts of a polyepoxide. By the composition, there can be obtained a curable-type resin composition which can form a coating layer which is excellent in acid resistance, abrasion resistance, yellowing resistance, and outer appearance, and which is curable at a low temperature. The present invention No. X relates to a polyester unsaturated monomer (a″) modified by a small amount of lactones in which less than 1 mol of &egr;-caprolactone is allowed to react with 1 mol of a radically polymerizable unsaturated monomers containing carboxylic group under the presence of an acidic catalyst, and relates to a method for the preparation thereof. By the method, there can be readily and industrially prepared the monomer in a short step.

  本发明涉及一种由少量内酯修饰的羟基烷基（甲基）丙烯酸酯组合物（a），其中具有两个或多个连续链（n≥2）的内酯单体的比例小于50％（GPC的面积％），其通过羟基烷基（甲基）丙烯酸酯与内酯的开环聚合获得，以及制备方法和使用其的丙烯酸聚醇树脂。其中，在公共使用的交联剂和其他常用组分的反应下，可以获得工业上平衡良好的高质量涂料剂、紫外线或电子束固化涂料剂、可用于反应改进剂的组合物等。本发明还涉及含有0.5-80重量份羟基烷基（甲基）丙烯酸酯组合物（a）修饰的丙烯酸聚醇树脂（A）和0.5-50重量份三聚氰胺树脂（B）的可固化树脂组合物（A）和（B）的总重量不超过100重量份的可固化树脂组合物（III）。此外，还涉及含有0.5-80重量份羟基烷基（甲基）丙烯酸酯组合物（a）修饰的丙烯酸聚醇树脂（A）和0.5-50重量份聚异氰酸酯化合物（B）的可固化树脂组合物（A）和（B）的总重量不超过100重量份的可固化树脂组合物（V）和（VI）。还涉及含有羟基烷基（甲基）丙烯酸酯组合物（a）修饰的丙烯酸聚醇树脂（A）和具有烷氧基硅基团的丙烯酸共聚物的热固性树脂组合物（VII）。此外，还涉及通过使少量内酯与羟基烷基（甲基）丙烯酸酯组合物（a）在存在酸性催化剂的情况下反应而得到的含有羧基丙烯酸酯组合物（a′）的修饰物，以及含有羧基丙烯酸酯组合物（a′）和聚环氧化合物的可固化树脂组合物（IX）。最后，还涉及通过在存在酸性催化剂的情况下使少于1摩尔的ε-己内酯与含有羧基团的自由基聚合可的不饱和单体反应而得到的少量内酯修饰的聚酯不饱和单体（a″）以及其制备方法。