methyl (2R)-5-chloro-2-propan-2-ylpent-4-enoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: methyl (2R)-5-chloro-2-propan-2-ylpent-4-enoate
• 化学式: C₉H₁₅ClO₂
• 分子量: 190.67
• InChiKey: BHFJTVFRXXWPLV-MRVPVSSYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• PREPARATION OF AN ESTERASE
  申请人：DSM IP Assets B.V.

  公开号：EP2171061A1

  公开（公告）日：2010-04-07
• US9309503B2
  申请人：——

  公开号：US9309503B2

  公开（公告）日：2016-04-12
• [EN] PREPARATION OF AN ESTERASE<br/>[FR] PRÉPARATION D'UNE ESTÉRASE
  申请人：DSM IP ASSETS BV

  公开号：WO2009004093A1

  公开（公告）日：2009-01-08

  The present invention relates to a recombinant E. coli strain characterized in that the organisms contains a gene coding for a protein having esterase activity. Such E. coli is suitable for the preparation of a protein with esterase activity, whereby the expression takes place without coexpression of GroEL and/or GroES from a plasmid. The expression of glutathione reductase and/or thioredoxin reductase may be abolished by mutation. Furthermore, the ability of the organism to grow under oxygen-rich conditions has been restored by mutation. The expression of the gene of the protein with esterase activity is unaccompanied by the expression of an additional gene encoding a heat shock chaperone protein.