2-Amino-6-azido-2-methylhexanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Amino-6-azido-2-methylhexanoic acid
• 英文别名: 2-amino-6-azido-2-methylhexanoic acid
• 化学式: C7H14N4O2
• 分子量: 186.21
• InChiKey: PYGYXUWPBHVSPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  77.7
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• BIOLOGICALLY ACTIVE PEPTIDOMIMETIC MACROCYCLES
  申请人：Aileron Therapeutics, Inc.

  公开号：EP2310407A2

  公开（公告）日：2011-04-20
• IMPROVED PEPTIDOMIMETIC MACROCYCLES
  申请人：Aileron Therapeutics, Inc.

  公开号：EP2488193A1

  公开（公告）日：2012-08-22
• Biologically Active Peptidomimetic Macrocycles
  申请人：Nash Huw M.

  公开号：US20110144303A1

  公开（公告）日：2011-06-16

  The present invention provides biologically active peptidomimetic macrocycles with improved properties relative to their corresponding polypeptides. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.
• PEPTIDOMIMETIC MACROCYCLES
  申请人：NASH Huw M.

  公开号：US20110223149A1

  公开（公告）日：2011-09-15

  The present invention provides biologically active peptidomimetic macrocycles with improved properties, such as protease resistance, relative to their corresponding polypeptides. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.
• [EN] BIOLOGICALLY ACTIVE PEPTIDOMIMETIC MACROCYCLES<br/>[FR] MACROCYCLES PEPTIDOMIMÉTIQUES BIOLOGIQUEMENT ACTIFS
  申请人：AILERON THERAPEUTICS INC

  公开号：WO2009126292A2

  公开（公告）日：2009-10-15

  The present invention provides biologically active peptidomimetic macrocycles with improved properties relative to their corresponding polypeptides The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.