(2S)-2-amino-3-[[15-[(1S)-1,2-dihydroxyethyl]-14,16-dioxononacosan-15-yl]oxy-hydroxyphosphoryl]oxypropanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-amino-3-[[15-[(1S)-1,2-dihydroxyethyl]-14,16-dioxononacosan-15-yl]oxy-hydroxyphosphoryl]oxypropanoic acid
• 化学式: C₃₄H₆₆NO₁₀P
• 分子量: 679.9
• InChiKey: MRGRDJRASBLUHX-NYDCQLBNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  46
• 可旋转键数：
  34
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  194
• 氢给体数：
  5
• 氢受体数：
  11

文献信息

• LIPID-BASED PLATINUM COMPOUNDS AND NANOPARTICLES
  申请人：Invictus Oncology Pvt. Ltd.

  公开号：EP3007709A2

  公开（公告）日：2016-04-20
• [EN] LIPID-BASED PLATINUM COMPOUNDS AND NANOPARTICLES<br/>[FR] COMPOSÉS DU PLATINE À BASE DE LIPIDES ET NANOPARTICULES CORRESPONDANTES
  申请人：INVICTUS ONCOLOGY PVT LTD

  公开号：WO2014201376A2

  公开（公告）日：2014-12-18

  The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to platinum based compounds comprising platinum moiety, linker moiety and lipid moiety and corresponding nanoparticles thereof. The disclosure further relates to synthesis of said platinum based compounds, nanoparticles and compositions comprising said platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by employing aforesaid carbene compounds, platinum based compounds, nanoparticles and compositions thereof.