[(3S)-1-chloro-3-hydroxy-4-octadec-9-enoyloxybutyl]phosphonic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: [(3S)-1-chloro-3-hydroxy-4-octadec-9-enoyloxybutyl]phosphonic acid
• 化学式: C₂₂H₄₂ClO₆P
• 分子量: 469.0
• InChiKey: CLVJEUIZSWXRRW-BGERDNNASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  30
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  104
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• [EN] DIAGNOSTIC AND THERAPEUTIC METHOD INVOLVING THE AUTOTAXIN-LYSOPHOSPHATIDIC ACID SIGNALLING PATHWAY<br/>[FR] MÉTHODE DIAGNOSTIQUE ET THÉRAPEUTIQUE IMPLIQUANT LA VOIE DE SIGNALISATION DE L'AXE AUTOTAXINE-ACIDE LYSOPHOSPHATIDIQUE
  申请人：BABRAHAM INST

  公开号：WO2015193669A1

  公开（公告）日：2015-12-23

  The invention relates to a method of diagnosing and treating hepatitis virus infection, such as hepatitis B or C virus infection, or a disease mediated by hepatitis infection, such as hepatitis B or C virus infection, by using the autotaxin-lysophosphatidic acid signalling pathway. The invention also relates to biomarkers for hepatitis infection, such as hepatitis B or C virus infection, or a disease mediated by hepatitis infection, such as hepatitis B or C virus infection.