[EN] AMINOACYL TRNA SYNTHETASES AND ORTHOGONAL TRNAS<br/>[FR] AMINOACYL-ARNT SYNTHÉTASES ET ARNT ORTHOGONAUX
申请人:ACIB GMBH AUSTRIAN CENTRE OF IND BIOTECHNOLOGY
公开号:WO2018185222A1
公开(公告)日:2018-10-11
The present invention relates to polynucleotides capable of catalyzing the aminoacylation of its cognate tRNA with aromatic or aliphatic amino acids to form an aminoacyl-tRNA, polypeptides encoded by such polynucleotides, vectors comprising such polynucleotides, host cells comprising such vectors, pairs of aminoacyl tRNA synthetases and cognate tRNAs, use of such compounds for catalyzing the aminoacylation of aromatic or aliphatic amino acids with corresponding tRNA to form an aminoacyl-tRNA, and methods for catalyzing the aminoacylation of cognate tRNA with aromatic or aliphatic amino acids to form an aminoacyl-tRNA.