4-Isocyanato-2-methylhex-2-enoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-Isocyanato-2-methylhex-2-enoic acid
• 英文别名: 4-isocyanato-2-methylhex-2-enoic acid
• 化学式: C₈H₁₁NO₃
• 分子量: 169.18
• InChiKey: FYHZMSIMTBHIJH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  66.7
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS
  申请人：Novartis AG

  公开号：EP2307190A1

  公开（公告）日：2011-04-13
• Silicone-Containing Polymeric Materials with Hydrolyzable Groups
  申请人：Chang Frank

  公开号：US20100014047A1

  公开（公告）日：2010-01-21

  The invention provides a silicone hydrogel contact lens including a hydrolyzable units. The hydrolyzable units can be converted by hydrolysis into a hydrophilic units which is capable of imparting the silicone hydrogel contact lens a hydrophilic surface without post-curing surface treatment. The invention also provides an actinically crosslinkable prepolymer including hydrolyzable units and use of the prepolymer of the invention. In addition, the invention provides a method for making wettable silicone hydrogel contact lens without posterior surface treatments other than hydrolysis.
• SILICONE-CONTAINING POLYMERIC MATERIALS WITH HYDROLYZABLE GROUPS
  申请人：Chang Frank

  公开号：US20120065331A1

  公开（公告）日：2012-03-15

  The invention provides a silicone hydrogel contact lens including a hydrolyzable units. The hydrolyzable units can be converted by hydrolysis into a hydrophilic units which is capable of imparting the silicone hydrogel contact lens a hydrophilic surface without post-curing surface treatment. The invention also provides an actinically crosslinkable prepolymer including hydrolyzable units and use of the prepolymer of the invention. In addition, the invention provides a method for making wettable silicone hydrogel contact lens without posterior surface treatments other than hydrolysis.
• US4515887A
  申请人：——

  公开号：US4515887A

  公开（公告）日：1985-05-07
• US4587204A
  申请人：——

  公开号：US4587204A

  公开（公告）日：1986-05-06