9-Methylsulfonylnonadec-9-enoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 9-Methylsulfonylnonadec-9-enoic acid
• 英文别名: 9-methylsulfonylnonadec-9-enoic acid
• 化学式: C₂₀H₃₈O₄S
• 分子量: 374.6
• InChiKey: LKEYYVMZBVVFDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  25
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  79.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• VINYL SUBSTITUTED FATTY ACIDS
  申请人：Complexa Inc.

  公开号：EP2280928B1

  公开（公告）日：2018-07-25
• PREVENTION, TREATMENT AND REVERSAL OF DISEASE USING THERAPEUTICALLY EFFECTIVE AMOUNTS OF ACTIVATED FATTY ACIDS
  申请人：Complexa, Inc.

  公开号：EP3355879A1

  公开（公告）日：2018-08-08
• TREATMENT OF PULMONARY ARTERIAL HYPERTENSION USING THERAPEUTICALLY EFFECTIVE ORAL DOSES OF 10-NITRO-9(E)-OCTADEC-9-ENOIC ACID
  申请人：Complexa Inc.

  公开号：US20200046669A1

  公开（公告）日：2020-02-13

  Various embodiments of this invention are directed to pharmaceutical compositions and methods for treating diseases, including focal segmental glomerulosclerosis or pulmonary arterial hypertension. The compositions of such embodiments include activated fatty acids such as alkyl substituted fatty acids, keto fatty acids and nitro fatty acids. The methods of various embodiments include administering an effective amount of 10-nitro-9(E)-octadec-9-enoic acid to treat such diseases.
• US9790167B2
  申请人：——

  公开号：US9790167B2

  公开（公告）日：2017-10-17