Ethyl 12-octadec-9-enoyloxyoctadecanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Ethyl 12-octadec-9-enoyloxyoctadecanoate
• 英文别名: ethyl 12-octadec-9-enoyloxyoctadecanoate
• 化学式: C₃₈H₇₂O₄
• 分子量: 593.0
• InChiKey: DBIQFRWQMAESEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  15
• 重原子数：
  42
• 可旋转键数：
  35
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] NEW NON-IONIC SURFACTANTS FOR SOLUBILIZING POORLY SOLUBLE MOLECULES<br/>[FR] NOUVEAUX TENSIOACTIFS NON IONIQUES DESTINES A SOLUBILISER DES MOLECULES FAIBLEMENT SOLUBLES
  申请人：ASTRAZENECA AB

  公开号：WO2004089869A1

  公开（公告）日：2004-10-21

  New non-ionic surfactants in the form of polyoxyalkylene glycol hydroxy fatty acid derivatives or monoalkylated polyoxyalkylene glycol hydroxy fatty acid derivatives having a polyoxyalkylene / alkyl polyoxyalkylene chain with a chain-length of 25 - 455 repeating units and a specified substituent on the hydroxy position of the specified hydroxy fatty acid, according to the general formula (I) CH3 - (CH2)x - CH - (CH2)y - CO - [-O - R3 - ]z - O - R1 R2 - O (I); wherein for example R1 is methyl, R2 is optionally substituted C14 - C22 acyl, alkyl, or alkenyl, R3 is ethylene, x is 2-12, y is 7-17, (x + y) is 3-19 and z is 25-57; advantageously prepared by involving an enzymatic process, formulations comprising them, their use as solubilizers and a process involving a hydrolytic enzyme for preparing them.

  新的非离子表面活性剂以聚氧烷基乙二醇羟基脂肪酸衍生物或单烷基化聚氧烷基乙二醇羟基脂肪酸衍生物的形式存在，具有聚氧烷基/烷基聚氧烷基链，链长为25-455个重复单元，并且在指定的羟基脂肪酸的羟基位置上具有特定的取代基，根据通式（I）CH3 -（CH2）x - CH -（ ）y - CO - [-O - R3 -]z - O - R1 R2 - O（I）；例如，其中R1为甲基，R2为可选的取代的C14 - C22酰基、烷基或烯基，R3为乙烯基，x为2-12，y为7-17，（x + y）为3-19，z为25-57；通过涉及酶过程有利地制备，包含它们的配方，它们作为溶剂的用途以及涉及水解酶制备它们的过程。
• Non-ionic surfactants for solubilizing poorly solubule molecules
  申请人：von Corswant Christian

  公开号：US20060287542A1

  公开（公告）日：2006-12-21

  New non-ionic surfactants in the form of polyoxyalkylene glycol hydroxy fatty acid derivatives or monoalkylated polyoxyalkylene glycol hydroxy fatty acid derivatives having a polyoxyalkylene / alkyl polyoxyalkylene chain with a chain-length of 25-455 repeating units and a specified substituent on the hydroxy position of the specified hydroxy fatty acid, according to the general formula (I) CH 3 —(CH 2 ) x —CH—(CH 2 ) y —CO—[—O—R 3 —] z —O—R 1 R 2 —O (I); wherein for example R 1 is methyl, R 2 is optionally substituted C 14 —C 22 acyl, alkyl, or alkenyl, R 3 is ethylene, x is 2-12, y is 7-17, (x+y) is 3-19 and z is 25-57; advantageously prepared by involving an enzymatic process, formulations comprising them, their use as solubilizers and a process involving a hydrolytic enzyme for preparing them.

  新的非离子表面活性剂采用聚氧烷基乙二醇羟基脂肪酸衍生物或单烷基化聚氧烷基乙二醇羟基脂肪酸衍生物形式，具有聚氧烷基/烷基聚氧烷基链，链长为25-455个重复单元，并且在指定羟基脂肪酸的羟基位置上具有指定的取代基，按照通式(I) CH3—(CH2)x—CH—( )y—CO—[—O—R3—]z—O—R1R2—O (I)；其中，例如R1为甲基，R2为可选取代的C14-C22酰基，烷基或烯基，R3为乙烯，x为2-12，y为7-17，(x+y)为3-19，z为25-57；通过涉及酶法的方法优选制备，包含它们的配方，它们作为溶解剂的用途以及涉及水解酶制备它们的方法。
• EP1615874A1
  申请人：——

  公开号：EP1615874A1

  公开（公告）日：2006-01-18
• NEW NON-IONIC SURFACTANTS FOR SOLUBILIZING POORLY SOLUBLE MOLECULES
  申请人：AstraZeneca AB

  公开号：EP1615874B1

  公开（公告）日：2013-12-25
• US7491836B2
  申请人：——

  公开号：US7491836B2

  公开（公告）日：2009-02-17