3,4-difluoro-4'-(4-ethylcyclohexyl)biphenyl | 134412-18-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,4-difluoro-4'-(4-ethylcyclohexyl)biphenyl
• 英文别名: 3,4-Difluoro-4'-(trans-4-ethylcyclohexyl)biphenyl；4-[4-(4-ethylcyclohexyl)phenyl]-1,2-difluorobenzene
• CAS: 134412-18-3
• 化学式: C₂₀H₂₂F₂
• 分子量: 300.391
• InChiKey: TYZNCUASDJPXMP-UHFFFAOYSA-N

物化性质

• 熔点：
  68-69℃

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 危险性防范说明：
  P264,P273,P280,P302+P352,P305+P351+P338,P332+P313,P337+P313,P362+P364,P501
• 危险性描述：
  H315,H319,H413

反应信息

• 作为产物：
  描述：

  反式-1-溴-4-(4-乙基环己烷)-苯 、 3,4-二氟苯硼酸 在 5%-palladium/activated carbon 、 四丁基溴化铵 、 sodium carbonate 、 三苯基膦 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 8.0h， 生成 3,4-difluoro-4'-(4-ethylcyclohexyl)biphenyl
  参考文献：
  名称：

  一种联苯类化合物的制备方法

  摘要：

  本发明提供了一种联苯类化合物的制备方法，属于有机合成领域，能够有效提高交叉偶联反应的选择性，增加产品收率。所述方法包括在碱、钯催化剂、季铵盐和三烃基膦类化合物的存在下，使芳香族卤代物和芳香族硼酸在溶剂中进行铃木反应。本发明可用于制备联苯类化合物。

  公开号：

  CN105481639B

文献信息

• LIQUID CRYSTAL COMPOUND HAVING CYCLOHEXENE RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20160280997A1

  公开（公告）日：2016-09-29

  A problem is to provide a liquid crystal compound satisfying at least one physical property such as high stability to heat and light, a high clearing point, low minimum temperature of liquid crystal phase, small viscosity, suitable optical anisotropy, large dielectric anisotropy, suitable elastic constant and excellent compatibility with other liquid crystal compounds, a liquid crystal composition containing the compound and a liquid crystal display device including the composition. A solution is a compound represented by formula (1). R 1 is alkyl having 1 to 10 carbons, rings A 1 , A 3 and A 4 are independently 1,4-phenylene, ring A 2 is a divalent group represented by any one of formulas (Ch), (Cx) and (ch). Z 1 , Z 2 , Z 3 and Z 4 are a single bond, X 1 is fluorine, L 1 and L 2 are fluorine, a, b and c are independently 0 or 1, and a sum of a, b and c is 0 or 1, for example.

  问题是提供一种液晶化合物，满足至少一种物理性质，如高热稳定性和耐光性、高清晰点、液晶相的低最低温度、低粘度、适当的光学各向异性、大介电各向异性、适当的弹性常数以及与其他液晶化合物的优良兼容性，一种含有该化合物的液晶组合物和包括该组合物的液晶显示装置。解决方案是由式（1）表示的化合物。R1是具有1到10个碳的烷基，环A1、A3和A4分别是1,4-苯撑，环A2是由任一式（Ch）、（Cx）和（ch）中的任一式表示的二价基团。Z1、Z2、Z3和Z4是单键，X1是氟，L1和L2是氟，a、b和c分别独立地为0或1，a、b和c的总和为0或1，例如。
• LIQUID CRYSTAL COMPOUND HAVING TETRACYCLE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20160340584A1

  公开（公告）日：2016-11-24

  A problem is to provide a liquid crystal compound satisfying at least one physical property such as high stability to heat and light, a high clearing point (or high maximum temperature), a low minimum temperature of a liquid crystal phase, small viscosity, suitable optical anisotropy, large dielectric anisotropy, a suitable elastic constant and excellent compatibility with other liquid crystal compounds, a liquid crystal composition containing the compound and a liquid crystal display device including the composition. A solution is a compound represented by formula (1). In which, R 1 is alkyl having 1 to 10 carbons or the like; Z 1 , Z 2 and Z 3 are independently a single bond, —COO—, —OCH 2 —, —CF 2 O— or the like, and at least one of Z 1 , Z 2 and Z 3 is —CF 2 O—; X 1 is hydrogen, fluorine, —CF 3 or —OCF 3 ; and L 1 , L 2 , L 3 and L 4 are independently hydrogen, fluorine or chlorine.

  一个问题是提供一种液晶化合物，满足至少一种物理性质，如对热和光的高稳定性，高清晰点（或高最高温度），液晶相的低最低温度，小粘度，适当的光学各向异性，大介电各向异性，适当的弹性常数和与其他液晶化合物的良好兼容性，包含该化合物的液晶组合物和包括该组合物的液晶显示装置。解决方案是由式（1）表示的化合物。其中，R1是含有1至10个碳或类似的烷基；Z1、Z2和Z3独立地是单键，—COO—，—OCH2—，—CF2O—或类似的，且Z1、Z2和Z3中至少一个是—CF2O—；X1是氢、氟、—CF3或—OCF3；L1、L2、L3和L4独立地是氢、氟或氯。
• COMPOUNDS HAVING A DIFLUOROCYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITIONS AND LIQUID CRYSTAL DISPLAY DEVICES
  申请人：JNC CORPORATION

  公开号：US20170240809A1

  公开（公告）日：2017-08-24

  The invention provides a liquid crystal compound satisfying at least one of physical properties such as a high stability to heat or light, a high clearing point (or a high maximum temperature), a low minimum temperature of a liquid crystal phase, a small viscosity, a suitable optical anisotropy, a small dielectric anisotropy, a suitable elastic constant and a good compatibility with other liquid crystal compounds, a liquid crystal composition including this compound, and a liquid crystal display device containing this composition. The invention provdes a compound represented by formula (1): where R 1 and R 2 is alkyl having 1 to 20 carbons or the like; one of L 1 and L 2 is both hydrogens, and the other is both fluorines; Z 1 and Z 2 are independently a single bond, —COO—, —OCO—, —OCH 2 —, —CH 2 O—, —CF 2 O—, —OCF 2 —, —CH 2 CH 2 —, —CH═CH—, —C≡C— or the like.

  该发明提供了一种液晶化合物，满足以下至少一种物理性质：对热或光的高稳定性，高清晰点（或高最高温度），液晶相的低最低温度，低粘度，适当的光学各向异性，小介电各向异性，适当的弹性常数以及与其他液晶化合物的良好兼容性，包括这种化合物的液晶组合物，以及含有这种组合物的液晶显示装置。该发明提供了一种由以下式（1）表示的化合物：其中R1和R2是具有1至20个碳原子的烷基或类似物；L1和L2中的一个是两个氢，另一个是两个氟；Z1和Z2独立地是单键，—COO—，—OCO—，—OCH2—，—CH2O—，—CF2O—，—OCF2—，—CH2CH2—，—CH═CH—，—C≡C—或类似物。
• COMPOUND HAVING A DIFLUOROCYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20170210991A1

  公开（公告）日：2017-07-27

  A liquid crystal compound represented by R 1 and R 2 are independently hydrogen, fluorine, chlorine, alkyl or the like; ring A 1 and ring A 3 are independently 1,4-cyclohexylene, 1,4-phenylene or the like; and A 2 is a divalent group represented by formula (A-1) or formula (A-2) Z 1 , Z 2 , Z 3 , Z 4 and Z 5 are independently a single bond, —COO— or the like; and a to d is 0, 1 or the like.

  由R1和R2独立表示为氢、氟、氯、烷基或类似物的液晶化合物；环A1和环A3独立表示为1,4-环己烯基、1,4-苯基或类似物；A2是由式（A-1）或式（A-2）表示的二价基团Z1、Z2、Z3、Z4和Z5独立表示为单键、—COO—或类似物；a至d为0、1或类似值。
• LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION EMPLOYING THE SAME
  申请人：DAXIN MATERIALS CORPORATION

  公开号：US20160222295A1

  公开（公告）日：2016-08-04

  A liquid crystal compound and a composition employing the same are provided. The liquid crystal compound has a structure represented by Formula (I) wherein R1, A1, A2, A3, A4, Z1, Z2, Z3, Z4, X, m, n, o, and p are defined as in the description.

  提供一种液晶化合物和应用该液晶化合物的组合物。该液晶化合物具有由式（I）表示的结构，其中R1、A1、A2、A3、A4、Z1、Z2、Z3、Z4、X、m、n、o和p的定义如描述中所述。