5-[3,3-dimethyl-2-[3-(1,3,3-trimethylindol-1-ium-2-yl)prop-2-enylidene]indol-1-yl]-N-[2-[2-[2-[2-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyethylamino]ethoxy]ethoxy]ethyl]pentanamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 5-[3,3-dimethyl-2-[3-(1,3,3-trimethylindol-1-ium-2-yl)prop-2-enylidene]indol-1-yl]-N-[2-[2-[2-[2-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyethylamino]ethoxy]ethoxy]ethyl]pentanamide
• 化学式: C43H63N4O9+
• 分子量: 780.0
• InChiKey: SSFADTFCQMBTSO-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  56
• 可旋转键数：
  21
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  165
• 氢给体数：
  6
• 氢受体数：
  11

文献信息

• FLUORESCENT DYE-LABELED GLUCOSE BIOPROBE, SYNTHESIS METHOD AND USAGE THEREOF
  申请人：Park Seung Bum

  公开号：US20100105149A1

  公开（公告）日：2010-04-29

  The present invention relates to a fluorescent dye-labeled glucose analog, and a synthesis method and usage of the same, and more particularly, to novel glucose α and β anomers in which a fluorescent dye is labeled by O-1-glycosylation, an asymmetric synthesis method of the anomers, a molecular bioimaging method of the anomers, and a screening method of curing or preventing drugs for diseases related to glucose metabolism.
• TWO PHOTON TRACER, METHOD FOR THE PREPARATION THEREOF AND THE USE THEREOF IN SCREENING ANTICANCER AGENTS
  申请人：PARK Seung Bum

  公开号：US20110059022A1

  公开（公告）日：2011-03-10

  Disclosed herein are compounds useful as two-photon tracers. Also, methods are provided for visualizing intracellular glucose uptake, screening anticancer agents, and diagnosing cancer using the compounds. They exhibit preferential uptake by cancer cells, penetrability sufficient to allow bright section images, high water solubility, high pH resistance and low toxicity in addition to applicability to living cells in deep tissues over a long period of time.
• US8632749B2
  申请人：——

  公开号：US8632749B2

  公开（公告）日：2014-01-21
• US8679854B2
  申请人：——

  公开号：US8679854B2

  公开（公告）日：2014-03-25
• US8772463B2
  申请人：——

  公开号：US8772463B2

  公开（公告）日：2014-07-08