3-(3-Hydroxypropoxycarbonyl)hept-2-enoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-(3-Hydroxypropoxycarbonyl)hept-2-enoic acid
• 英文别名: 3-(3-hydroxypropoxycarbonyl)hept-2-enoic acid
• 化学式: C₁₁H₁₈O₅
• 分子量: 230.26
• InChiKey: OQEFODGZCXVFKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  16
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  83.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• HYDROGEL BASED ON COPOLYMERS CONTAINING SILICONE
  申请人：Breiner Christine Maria

  公开号：US20110046332A1

  公开（公告）日：2011-02-24

  The invention relates to a hydrogel which is a copolymer formed from a polymerizable monomer mixture which contains a) 10-65 mol % of at least one hydrophobic vinyl monomer of the formula I in which R 1 is hydrogen or methyl, p is an integer from 1 to 8, whose hydroxyl groups are present in protected form, b) 25-70 mol % of at least one silicone-containing (meth)acrylate, vinyl carbonate or vinyl carbamate monomer, c) 0-25 mol % of at least one hydrophilic vinyl monomer and d) 0-10 mol % of at least one crosslinker, based on the total amount of monomers a) to c), and where the hydroxyl groups of the segments formed by the monomers a) in the hydrogel are present in protected form or in free form. The hydrogel can be used to produce contact lenses or intraocular lenses.