N-Octyl B-D-maltoside

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-Octyl B-D-maltoside
• 英文别名: 2-[4,5-dihydroxy-2-(hydroxymethyl)-6-octoxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• 化学式: C₂₀H₃₈O₁₁
• 分子量: 454.5
• InChiKey: MASIZQYHVMQQKI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  31
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  179
• 氢给体数：
  7
• 氢受体数：
  11

文献信息

• ONE-POT SYNTHESIS OF ALPHA/BETA-O-GLYCOLIPIDS
  申请人：Gervay-Hague Jacquelyn

  公开号：US20110251378A1

  公开（公告）日：2011-10-13

  The present invention provides a one-pot method of preparing an unprotected α-O-glycolipid. The first step involves contacting a protected α-iodo sugar with a catalyst and a lipid comprising a hydroxy group, under conditions sufficient to prepare a protected α-O-glycolipid. The second step involves deprotecting the protected α-O-glycolipid under conditions sufficient to prepare the unprotected α-O-glycolipid, wherein the contacting and deprotecting steps are performed in a single vessel. The present invention also provides a one-pot method of preparing an unprotected β-O-glycolipid following the steps for the preparation of the unprotected α-O-glycolipid.

  本发明提供了一种制备未保护的α-O-糖脂的一锅法。第一步涉及将受保护的α-碘糖与催化剂和含有羟基的脂质接触，在足够条件下制备受保护的α-O-糖脂。第二步涉及在足够条件下去保护受保护的α-O-糖脂，从而制备未保护的α-O-糖脂，其中接触和去保护步骤在单个容器中执行。本发明还提供了一种制备未保护的β-O-糖脂的一锅法，其遵循制备未保护的α-O-糖脂的步骤。
• ONE-POT SYNTHESIS OF ALPHA/BETA-O-CLYCOLIPIDS
  申请人：The Regents of the University of California

  公开号：US20140221633A1

  公开（公告）日：2014-08-07

  The present invention provides a one-pot method of preparing an unprotected α-O-glycolipid. The first step involves contacting a protected α-iodo sugar with a catalyst and a lipid comprising a hydroxy group, under conditions sufficient to prepare a protected α-O-glycolipid. The second step involves deprotecting the protected α-O-glycolipid under conditions sufficient to prepare the unprotected α-O-glycolipid, wherein the contacting and deprotecting steps are performed in a single vessel. The present invention also provides a one-pot method of preparing an unprotected β-O-glycolipid following the steps for the preparation of the unprotected α-O-glycolipid.

  本发明提供了一种制备未保护的α-O-糖脂的一锅法。第一步涉及将受保护的α-碘糖与催化剂和含有羟基的脂质接触，在足够的条件下制备受保护的α-O-糖脂。第二步涉及在足够的条件下去除受保护的α-O-糖脂的保护基，制备未保护的α-O-糖脂，其中接触和去保护步骤在单个容器中进行。本发明还提供了一种制备未保护的β-O-糖脂的一锅法，遵循制备未保护的α-O-糖脂的步骤。
• REAGENT KIT, MEASUREMENT KIT, AND MEASUREMENT METHOD
  申请人：FUJIFILM Corporation

  公开号：US20200408773A1

  公开（公告）日：2020-12-31

  An object of the present invention is to provide a reagent kit, a measurement kit, and a measurement method for measuring serum amyloid A, which enable measurement having a high correlation of an increase in signal with respect to the concentration of serum amyloid A. According to the present invention, provided is a reagent kit for measuring serum amyloid A, including first particles having a label and modified with a first binding substance having a property of specifically binding to serum amyloid A, and at least one nonionic surfactant having an HLB value of 17 to 20, which is defined by (inorganicity value/organicity value)×10 and a molecular weight of 1000 or less.
• US8624006B2
  申请人：——

  公开号：US8624006B2

  公开（公告）日：2014-01-07
• US9586984B2
  申请人：——

  公开号：US9586984B2

  公开（公告）日：2017-03-07