12,12-Dimethyltridecanal

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 12,12-Dimethyltridecanal
• 英文别名: 12,12-dimethyltridecanal
• 化学式: C₁₅H₃₀O
• 分子量: 226.4
• InChiKey: ZXCJSMJEZYJLJI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• NATURAL SAPONIN-BASED SYNTHETIC IMMUNOADJUVANTS
  申请人：THE UAB RESEARCH FOUNDATION

  公开号：US20150050319A1

  公开（公告）日：2015-02-19

  The present disclosure encompasses QS-21-based structurally-defined adjuvants to address the need for stronger, safer, and easier-to-access adjuvants. The new compositions can provide tools for addressing long-standing mechanistic questions concerning saponin immune-potentiation through structure-activity-relationship (SAR) studies. Most advantageously, the compounds of the disclosure may be formulated into pharmaceutically acceptable compositions, including vaccines that may be delivered to a subject human or animal subject. The compounds can then act as, for example, an adjuvant to augment an immunological response to a vaccine immunogen.