4-fluoro-3-propoxybenzaldehyde

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-fluoro-3-propoxybenzaldehyde
• 英文别名: 4-Fluoro-3-propoxybenzaldehyde
• 化学式: C₁₀H₁₁FO₂
• 分子量: 182.195
• InChiKey: UUJUUQFTURUNQL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA.
  申请人：Inventiva

  公开号：EP3606921A1

  公开（公告）日：2020-02-12
• NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA
  申请人：INVENTIVA

  公开号：US20200115353A1

  公开（公告）日：2020-04-16

  The invention relates to compounds of formula: wherein R 1 to R 7 are as defined in the description. These compounds are useful as inhibitors of the YAP/TAZ-TEAD interaction.
• [EN] NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA.<br/>[FR] NOUVEAUX COMPOSÉS INHIBITEURS DE L'INTERACTION YAP/TAZ-TEAD ET LEUR UTILISATION DANS LE TRAITEMENT DU MÉSOTHÉLIOME MALIN
  申请人：INVENTIVA

  公开号：WO2018185266A1

  公开（公告）日：2018-10-11

  The invention relates to compounds of formula: wherein R1 to R7 are as defined in the description. These compounds are useful as inhibitors of the YAP/TAZ-TEAD interaction.