3-(2-pyridyl)-5,6-bis(2-(5-furyl sulfonic acid))-1,2,4-triazine | 90691-98-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 3-(2-pyridyl)-5,6-bis(2-(5-furyl sulfonic acid))-1,2,4-triazine
• 英文别名: NSC 601364；5,5'-(3-(pyridin-2-yl)-1,2,4-triazine-5,6-diyl)difuran-2-sulfonic acid；5-[3-Pyridin-2-yl-6-(5-sulfofuran-2-yl)-1,2,4-triazin-5-yl]furan-2-sulfonic acid
• CAS: 90691-98-8
• 化学式: C₁₆H₁₀N₄O₈S₂
• 分子量: 450.409
• InChiKey: JADQARCBSBASKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  203
• 氢给体数：
  2
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  2-吡啶氨基腙 在 硫酸 作用下， 以 异丙醇 为溶剂， 反应 1.25h， 生成 3-(2-pyridyl)-5,6-bis(2-(5-furyl sulfonic acid))-1,2,4-triazine
  参考文献：
  名称：

  Hennessy, Douglas J.; Reid, Gary R.; Smith, Frank E., Canadian Journal of Chemistry, 1984, vol. 62, p. 721 - 724

  摘要：

  DOI：

文献信息

• Quantitative analysis apparatus and method
  申请人：BIO-METRICS SYSTEMS, INC.

  公开号：EP0088636A2

  公开（公告）日：1983-09-14

  A method and apparatus for the quantitative determination of an analyte in a liquid employs a liquid-permeable solid medium defining a liquid flow path. The medium includes a number of reactant-containing reaction zones spaced apart along the flow path and in which reaction occurs with the analyte or an analyte derivative (e.g., a labelled analyte) to result in the formation of a predetermined product. Detector means are employed to detect analyte, analyte derivative, reactant or predetermined product in the reaction zones, the number of such zones in which such detection occurs indicating the amount of analyte in the liquid.

  一种定量测定液体中分析物的方法和装置采用了一种限定液体流动路径的液体渗透性固体介质。介质包括若干沿流动路径间隔开的含反应物的反应区，在这些反应区中与被分析物或被分析物衍生物（如标记的被分析物）发生反应，形成预定产物。检测器用于检测反应区中的被分析物、被分析物衍生物、反应物或预定产物，发生这种检测的反应区的数量表示液体中被分析物的数量。
• NOVEL COMPOUND, AND METHOD FOR MEASURING IRON CONCENTRATION BY USING NOVEL COMPOUND AS CHELATE COLOR FORMER
  申请人：WAKO PURE CHEMICAL INDUSTRIES LIMITED

  公开号：EP2910607A1

  公开（公告）日：2015-08-26

  The present invention addresses the problem of providing a chelate color former which can measure the concentration of iron with high sensitivity and with low blank values when measuring the concentration of iron, and an iron concentration measurement method and kit that use this chelate color former. The present invention relates to: a compound represented by following formula [1] or a salt thereof wherein, R1 and R2 each independently represent -SO3H or -CO2H; an iron concentration measurement method in which the compound is used as a chelate color former, the compound is brought into contact with iron in a sample, and the concentration of iron in the sample is measured on the basis of the degree of resulting color development; and a kit to be used therein.

  本发明要解决的问题是提供一种在测量铁浓度时灵敏度高且空白值低的螯合显色剂，以及使用该螯合显色剂的铁浓度测量方法和试剂盒。本发明涉及：由下式[1]代表的化合物或其盐类 其中，R1 和 R2 各自独立地代表-SO3H 或-CO2H；一种铁浓度测量方法，其中该化合物被用作螯合显色剂，该化合物与样品中的铁接触，并根据所产生的显色程度测量样品中的铁浓度；以及用于其中的试剂盒。
• Methods and apparatus for accelerated orthokeratology
  申请人：——

  公开号：US20010016731A1

  公开（公告）日：2001-08-23

  An accelerated method of orthokeratology includes the steps of softening of the cornea with a softening agent, applying a mold to reshape the cornea to a desired anterior curvature, and rapidly restabilizing or “fixing” the corneal tissues so that the cornea retains its new configuration. A chemical softening agent, such as glutaric anhydride is applied to the cornea to soften the cornea, after which a specially designed mold of predetermined curvature and configuration is applied to the cornea. Slight downward pressure is applied to the mold for a predetermined period of time to re-shape the cornea. The mold is maintained in position while a stabilizing agent, such as a UV light source, is positioned above the mold. The stabilizing agent, i.e. UV light, is applied to the cornea for a predetermined time, wherein the stabilizing agent immediately restabilizes the corneal tissue so that the cornea immediately retains its shape upon removal of the mold. The stabilization process can also be used for patients having already undergone traditional orthokeratology to eliminate the need to continue wearing a retainer to maintain the shape of the cornea.

  角膜矫形术的加速方法包括以下步骤：用软化剂软化角膜，使用模具将角膜重塑成所需的前弧度，并迅速重新稳定或 "固定 "角膜组织，使角膜保持新的形态。在角膜上涂抹化学软化剂（如戊二酸酐）以软化角膜，然后在角膜上涂抹专门设计的具有预定弧度和结构的模具。在预定时间内对模具施加轻微的向下压力，以重新塑形角膜。将稳定剂（如紫外线光源）置于模具上方时，模具将保持在原位。将稳定剂（即紫外线）照射到角膜上，持续预定的时间，其中稳定剂会立即重新稳定角膜组织，使角膜在移除模具后立即保持其形状。稳定过程也可用于已接受传统角膜矫形术的患者，使其无需继续佩戴保持器来保持角膜的形状。
• METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY
  申请人：Ista Pharmaceuticals, Inc

  公开号：EP1051655B1

  公开（公告）日：2005-09-28
• METHOD OF DETERMINING IRON CONCENTRATION
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：EP1881328B1

  公开（公告）日：2010-06-02