2-Ethylbutyric acid, 2-methylpentyl ester

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Ethylbutyric acid, 2-methylpentyl ester
• 英文别名: 2-methylpentyl 2-ethylbutanoate
• 化学式: C₁₂H₂₄O₂
• 分子量: 200.32
• InChiKey: CMLILCIKJQYHFF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Prodrugs of NH-Acidic Compounds
  申请人：Alkermes Pharma Ireland Limited

  公开号：US20170015659A1

  公开（公告）日：2017-01-19

  The invention provides a method of sustained delivery of a lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug by administering to a patient an effective amount of a prodrug compound of the invention wherein upon administration to the patient, release of the parent drug from the prodrug is sustained release. Prodrug compounds suitable for use in the methods of the invention are labile conjugates of parent drugs that are derivatized through carbonyl linked prodrug moieties. The prodrug compounds of the invention can be used to treat any condition for which the lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug is useful as a treatment.
• Process for Synthesizing Oxidized Lactam Compounds
  申请人：Alkermes Pharma Ireland Limited

  公开号：US20170267639A1

  公开（公告）日：2017-09-21

  The invention provides a method for the synthesis of dehydrogenated lactam drugs of Formula I:
• US9650341B2
  申请人：——

  公开号：US9650341B2

  公开（公告）日：2017-05-16
• US9670200B2
  申请人：——

  公开号：US9670200B2

  公开（公告）日：2017-06-06