[4,5-Diacetyloxy-6-[3,4-diacetyloxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxyoxan-2-yl]methyl acetate | 35867-25-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: [4,5-Diacetyloxy-6-[3,4-diacetyloxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxyoxan-2-yl]methyl acetate
• CAS: 35867-25-5
• 化学式: C₂₂H₃₂O₁₆
• 分子量: 552.5
• InChiKey: AHLIHMGXFJRKSY-UHFFFAOYSA-N

物化性质

• 溶解度：
  可溶于氯仿、可溶于二氯甲烷、乙酸乙酯

计算性质

• 辛醇/水分配系数(LogP)：
  -2.7
• 重原子数：
  38
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  220
• 氢给体数：
  3
• 氢受体数：
  16

文献信息

• [EN] AN IMPROVED PROCESS FOR THE PREPARATION OF 1, 6-DICHLORO-1, 6-DIDE0XY-BETA-D-FRUCT0FURAN0SYL-4-CHL0R0-4-DE0XY-ALPHA-GALACT0PY RANOSIDE<br/>[FR] PROCÉDÉ AMÉLIORÉ D'OBTENTION DE 1,6-DICHLORO-1,6-DIDÉOXY-ß-D-FRUCTOFURANOSYL-4- CHLORO-4- DÉOXY-a-GALACTOPYRANOSIDE
  申请人：ALEMBIC LTD

  公开号：WO2009087677A1

  公开（公告）日：2009-07-16

  The present invention relates to an improved process for the preparation of 2, 3, 6, 3', 4'- Penta-O-acetylsucrose 6-PAS), formula (V) and sucralose, formula (I).

  本发明涉及一种改进的制备2,3,6,3',4'-五-O-乙酰基蔗糖6-磷酸酯(6-PAS)（式(V)）和三氯蔗糖（式(I)）的方法。
• [EN] AN IMPROVED PROCESS FOR THE PREPARATION OF 2, 3, 6, 3 ', 4 ' - PENTA- O -ACETYLSUCROSE<br/>[FR] PROCÉDÉ AMÉLIORE D'OBTENTION DE 2, 3, 6, 3 ', 4 ' - PENTA- O -ACÉTYLSUCROSE
  申请人：ALEMBIC LTD

  公开号：WO2009087676A1

  公开（公告）日：2009-07-16

  The present invention relates to an improved process for the preparation of 2, 3, 6, 3', 4'- Penta-O-acetylsucrose (6-PAS) (V) from sucrose. Formula (V)

  本发明涉及一种改进的从蔗糖制备2,3,6,3',4'-五-O-乙酰基蔗糖(6-PAS)(V)的过程。公式(V)。
• Process for purification of sucralose
  申请人：Deshpande Balwant Pandurang

  公开号：US20070160732A1

  公开（公告）日：2007-07-12

  The present invention relates to a process for the purification of Sucralose of formula (I) which comprises acetylation of substantially impure Sucralose to its penultimate intermediate 4,1′,6′-trichloro-4,1′,6′-trideoxy galactosucrose penta-acetate (TOPSA) of formula (VI) followed by purification of TOPSA and then deacetylation of purified TOPSA.
• US7741477B2
  申请人：——

  公开号：US7741477B2

  公开（公告）日：2010-06-22
• [EN] COST EFFICIENT PROCESS FOR PREPARATION OF SUCRALOSE<br/>[FR] PROCESSUS RENTABLE DE PREPARATION DE SUCRALOSE
  申请人：ALEMBIC LTD

  公开号：WO2010013157A2

  公开（公告）日：2010-02-04

  The present invention relates to cost efficient process for preparation of sucralose. The present invention relates to recovery of the reagents from feed mixture obtained in various steps of sucralose. Particularly, the present invention relates to recovery of trityl chloride, β-picoline, triphenylphosphine oxide (TPPO) and methyl acetate.