N,N'-dipropylbutanediamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N,N'-dipropylbutanediamide
• 化学式: C₁₀H₂₀N₂O₂
• 分子量: 200.28
• InChiKey: BPGXZVVFYWUIEB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Substituted hydroxyethylamines
  申请人：John Varghese

  公开号：US20060106256A1

  公开（公告）日：2006-05-18

  This invention relates to prodrugs of a class of amine compounds which are useful in the treatment of Alzheimer's disease and similar diseases.

  本发明涉及一类氨基化合物的前药，该类化合物在治疗阿尔茨海默病和类似疾病方面具有用途。
• Compounds to treat Alzheimer's disease
  申请人：Fang Y. Lawrence

  公开号：US20070213407A1

  公开（公告）日：2007-09-13

  The present invention is substituted amines of formula (X) useful in treating Alzheimer's disease and other similar diseases.

  本发明涉及一种公式（X）的取代胺，用于治疗阿尔茨海默病和其他类似疾病。
• N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives
  申请人：John Varghese

  公开号：US20070213316A1

  公开（公告）日：2007-09-13

  Disclosed are compounds of the formula wherein the variables R N , R C , R 1 , R 25 , R 2 , and R 3 are as defined herein. These compounds have activity as inhibitors of beta-secretase and are therefore useful in treating a variety of discorders such as Alzheimer's Disease.

  本发明揭示了以下式子的化合物：其中变量RN，RC，R1，R25，R2和R3如本文所定义。这些化合物具有抑制β-分泌酶的活性，因此可用于治疗多种疾病，例如阿尔茨海默病。
• Thermoplastic resin composition
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0382548A2

  公开（公告）日：1990-08-16

  A thermoplastic resin composition which comprises: 100 parts by weight of a composition comprising (A) 5 - 95% by weight of a polyphenylene ether and (B) 95 - 5% by weight of a thermoplastic polyester, (C) 0.5 - 100 parts by weight of an aromatic polycarbonate resin, and (E) 0.01 - 10 parts by weight of an amino resin obtainable by at least partially modifying with an alcohol an addition reaction product of formaldehyde and at least one compound selected from melamine, guanamine and urea.

  一种热塑性树脂组合物，它包括 100 重量份的组合物，其中包括 (A) 5-95%（重量百分比）的聚苯醚和 (B) 95-5%（重量百分比）的热塑性聚酯、 (C) 0.5 - 100 份（重量百分比）芳香族聚碳酸酯树脂，和 (E) 0.01 - 10 份(重量)氨基树脂，可通过至少部分用醇改性甲醛与至少一种选 自三聚氰胺、鸟嘌呤胺和尿素的化合物的加成反应产物而获得。
• US5116906A
  申请人：——

  公开号：US5116906A

  公开（公告）日：1992-05-26