Bis(dimethylamino)-o-tolylphosphane | 289670-84-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Bis(dimethylamino)-o-tolylphosphane
• 英文别名: ortho-bis(dimethylamino)phosphinotoluene；bis(dimethylamino)(o-tolyl)phosphine；N-[dimethylamino-(2-methylphenyl)phosphanyl]-N-methylmethanamine
• CAS: 289670-84-4
• 化学式: C₁₁H₁₉N₂P
• 分子量: 210.259
• InChiKey: DOIDHABSDGLQGW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (S)-(+)-2-(苯胺甲基)吡咯烷 、 Bis(dimethylamino)-o-tolylphosphane 以 甲苯 为溶剂， 反应 2.0h， 以89%的产率得到(5S)-2-(2-methylphenyl)-3-phenyl-1,3-diaza-2-phosphabicyclo[3.3.0]octane
  参考文献：
  名称：

  新型高活性手性磷钯环催化剂。Pd(iv) 中间体的首次分离和表征

  摘要：

  描述了一种新的活性 P*-活性 phosphapaladacycle 的合成和表征及其在降冰片烯的不对称加氢芳基化中的成功应用，其周转数 (TONs) 高达 1010。

  DOI：

  10.1039/b005521m
• 作为产物：
  描述：

  邻甲苯基溴化镁 、 双(二甲基氨)氯膦 以 四氢呋喃 为溶剂， 以78%的产率得到Bis(dimethylamino)-o-tolylphosphane
  参考文献：
  名称：

  Highly Efficient Phosphapalladacyclic Catalysts for the Hydroarylation of Norbornene

  摘要：

  DOI：

  10.1002/1521-3773(20000602)39:11<1946::aid-anie1946>3.0.co;2-i

文献信息

• Asymmetric Hydrogenation of Ketones Using a Ruthenium(II) Catalyst Containing BINOL-Derived Monodonor Phosphorus-Donor Ligands
  作者：Yingjian Xu、Nat W. Alcock、Guy J. Clarkson、Gordon Docherty、Gary Woodward、Martin Wills

  DOI：10.1021/ol0481840

  日期：2004.10.1

  [structure: see text] A series of ruthenium(II) complexes containing BINOL-based monodonor phosphorus ligands have been prepared and applied to the asymmetric catalysis of the hydrogenation of aryl/alkyl ketones. The best ligands for this application are those which contain an aromatic groups with either a methoxide or bromide on the ortho position. Using these ligands, alcohols with ee's of up to

  [结构：见正文]制备了一系列含BINOL基单供体磷配体的钌（II）配合物，并将其用于芳基/烷基酮氢化的不对称催化。对于该应用而言，最好的配体是那些含有在邻位带有甲氧基或溴化物的芳族基团的配体。使用这些配体，可以形成ee高达99％的醇。
• Enantiomerically pure cyclopalladated diazaphospholidine
  作者：Valery V. Dunina、Olga N. Gorunova、Valeriya A. Stepanova、Pavel A. Zykov、Michail V. Livantsov、Yuri K. Grishin、Andrey V. Churakov、Lyudmila G. Kuz’mina

  DOI：10.1016/j.tetasy.2007.09.005

  日期：2007.9

  Enantiomerically pure (S)-2-(anilinomethyl)pyrrolidine (S)-2 was obtained from (S)-proline using a modified four-step procedure in a total yield of 56%. Diamine (S)-2 was converted to diazaphospholidine (S)-1 using (0)TolP(NMe2)(2). The enantiomeric purity of ligand (S)-1 and diamine (S)-2 was determined by P-31 and H-1 NMR spectroscopy, respectively, using a CN-palladacycle for their chiral derivatization. Direct cyclopalladation of (S)-1 using Pd(OAc)(2) in toluene under mild conditions regioselectively afforded the cyclopalladated complex with the (sp(2))C-Pd bond. The aromatic C-H bond activation was confirmed by NMR spectral data and X-ray diffraction study of the PPh3 derivative of the new P*,C*,N*-chiral phosphapalladacycle. (C) 2007 Elsevier Ltd. All rights reserved.
• METHOD FOR PRODUCING NORBORNENE DERIVATIVE
  申请人：Komatsu Shinichi

  公开号：US20100197970A1

  公开（公告）日：2010-08-05

  A method for producing a norbornene derivative wherein, in the presence of palladium and at least one selected from phosphorus compounds represented by the following General Formulae (1) and (2): [in Formula (1), R 1 , R 2 , R 3 and R 4 each independently represent a hydrogen atom or the like, and R 5 and R 6 each independently represent a branched chain saturated hydrocarbon group having 3 to 10 carbon atoms or the like], and [in Formula (2), R 7 represents a branched chain saturated hydrocarbon group having 3 to 10 carbon atoms], a norbornadiene derivative represented by the following General Formula (3): [in Formula (3), R 8 , R 9 , R 10 , R 11 and R 12 each independently represent a hydrogen atom or the like, l represents an integer of 0 or 1, m represents an integer of 0 or 1, and n represents an integer of 0 or 1], and a bromine compound represented by the following General Formula (4): [Chemical Formula 4] Br—Z—R 13 (4) [in Formula (4), Z represents a phenylene group or the like, and R 13 represents a hydrogen atom or the like] are reacted with each other, to thereby obtain a norbornene derivative represented by the following General Formula (5): [in Formula (5), R 14 , R 15 , R 16 , R 17 and R 18 each independently represent a hydrogen atom or the like, Z represents a phenylene group or the like, R 19 represents a hydrogen atom or the like, l represents an integer of 0 or 1, m represents an integer of 0 or 1, and n represents an integer of 0 or 1], the norbornene derivative having a configuration of a substituent represented by Z in General Formula (5) that is an exo configuration.
• TETRACARBOXYLIC DIANHYDRIDE, POLYAMIC ACID, POLYIMIDE, METHODS FOR PRODUCING THE SAME, AND POLYAMIC ACID SOLUTION
  申请人：JX NIPPON OIL & ENERGY CORPORATION

  公开号：US20170044322A1

  公开（公告）日：2017-02-16

  A tetracarboxylic dianhydride, which is a compound represented by the following general formula (1): [in the formula (1), A represents a divalent aromatic group in which the number of carbon atoms forming an aromatic ring is 6 to 30 or the like, and multiple R 1 s each independently represent a hydrogen atom or the like].
• US4145559A
  申请人：——

  公开号：US4145559A

  公开（公告）日：1979-03-20