(3-Methylpiperidin-1-yl)(morpholin-4-yl)methanone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: (3-Methylpiperidin-1-yl)(morpholin-4-yl)methanone
• 英文别名: (3-methylpiperidin-1-yl)-morpholin-4-ylmethanone
• 化学式: C₁₁H₂₀N₂O₂
• mdl: MFCD02859859
• 分子量: 212.29
• InChiKey: VYDTVSFJMAGVDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.909
• 拓扑面积：
  32.8
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Compounds for the treatment of inflammatory diseases
  申请人：Hoenke Christoph

  公开号：US20070259846A1

  公开（公告）日：2007-11-08

  Dihydrothienopyrimidines of formula 1 and the pharmacologically acceptable salts, enantiomers, racemates, hydrates, or solvates thereof, which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.

  化学式1的二氢噻吡嘧啶及其药理学上可接受的盐、对映体、消旋体、水合物或溶剂合物，适用于治疗呼吸道或胃肠道不适或疾病、关节、皮肤或眼睛的炎症性疾病、外周或中枢神经系统疾病或癌症，以及含有这些化合物的药物组合物。
• COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES
  申请人：HOENKE Christoph

  公开号：US20100197656A1

  公开（公告）日：2010-08-05

  Dihydrothienopyrimidines of formula 1 and the pharmacologically acceptable salts, enantiomers, racemates, hydrates, or solvates thereof, which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.

  公式1中的二氢噻唑嘧啶及其药理学上可接受的盐、对映体、消旋体、水合物或溶剂化物，适用于治疗呼吸或胃肠疾病、关节、皮肤或眼睛的炎症性疾病、外周或中枢神经系统疾病或癌症，以及含有这些化合物的制药组合物。
• Heterocyclic Compounds Which Modulate The CB2 Receptor
  申请人：Bartolozzi Alessandra

  公开号：US20110312944A1

  公开（公告）日：2011-12-22

  Compounds which modulate the CB2 receptor are disclosed. Compounds according to the invention bind to and are agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.

  本发明揭示了调节CB2受体的化合物。根据本发明，这些化合物与CB2受体结合并作为激动剂，用于治疗炎症。那些作为激动剂的化合物还可用于治疗疼痛。
• US7511045B2
  申请人：——

  公开号：US7511045B2

  公开（公告）日：2009-03-31
• US7723341B2
  申请人：——

  公开号：US7723341B2

  公开（公告）日：2010-05-25