3-(Methylhydrazinylidene)inden-1-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 3-(Methylhydrazinylidene)inden-1-one
• 化学式: C₁₀H₁₀N₂O
• 分子量: 174.2
• InChiKey: NRDYZLSIZYUHNH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  41.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Compounds and methods for the treatment of ubiquitin conjugating disorders
  申请人：Banerjee Amit

  公开号：US20060035890A1

  公开（公告）日：2006-02-16

  The present invention provides methods for identifying compounds that selectively bind one or more active sites within an ubiquitin conjugating enzyme. The compounds identified by the methods are useful in the treatment of disorders attributed to dysregulated ubiquitin conjugating enzyme function, specifically in hyperproliferative disorders.
• Method for the treatment of a ubiquitin conjugating disorder
  申请人：Banerjee Amit

  公开号：US20070191488A1

  公开（公告）日：2007-08-16

  The present invention provides methods for identifying compounds that selectively bind one or more active sites within an ubiquitin conjugating enzyme. The compounds identified by the methods are useful in the treatment of disorders attributed to dysregulated ubiquitin conjugating enzyme function, specifically in hyperproliferative disorders.
• US8003572B2
  申请人：——

  公开号：US8003572B2

  公开（公告）日：2011-08-23