7-亚氨基吩噻嗪-3-胺盐酸盐 | 635-76-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 中文名称: 7-亚氨基吩噻嗪-3-胺盐酸盐
• 英文名称: thionine cloride
• 英文别名: thionine；thionin；thrombin；thionine hydrochloride；thionine chloride；Thionin-hydrochlorid；hydron;7-iminophenothiazin-3-amine;chloride
• CAS: 635-76-7
• 化学式: C₁₂H₉N₃S*ClH
• 分子量: 263.75
• InChiKey: PVPBBTJXIKFICP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.35
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  89.3
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  7-亚氨基吩噻嗪-3-胺盐酸盐 在 铁粉 作用下， 以 硫酸 为溶剂， 生成 leucothionine
  参考文献：
  名称：

  The Photoreduction of Thionine and Surfactant Thionine by Iron(II) in Anionic Micelles and Microemulsions

  摘要：

  AbstractThe rate constants for the iron(II)‐thionine and surfactant thionine system have been determined in aqueous solution, sodium dodecyl sulfate (SDS) micelles, and in a mineral oil‐in‐water microemulsion stabilized by sodium cetyl sulfate (SCS) and 1‐pentanol. The triplet lifetimes are all in the range 7–9 μs. The rate constant for electron transfer quenching of triplet thionine by iron(II) is higher in the anionic media due to a higher local Fe2+ concentration. However, the back reaction between semithionine and iron(III) is not similarly enhanced in the presence of micelles or microemulsion. The dismutation of semithionine is a little slower in microemulsion than in water, but over two orders of magnitude slower in SDS micelles. The quantum yield of thionine triplet formation, determined for surfactant thionine in SCS microemulsion, approaches unity.

  DOI：

  10.1002/bbpc.19850890513
• 作为产物：
  描述：

  semithionine 以 硫酸 为溶剂， 生成 7-亚氨基吩噻嗪-3-胺盐酸盐 、 leucothionine
  参考文献：
  名称：

  The Photoreduction of Thionine and Surfactant Thionine by Iron(II) in Anionic Micelles and Microemulsions

  摘要：

  AbstractThe rate constants for the iron(II)‐thionine and surfactant thionine system have been determined in aqueous solution, sodium dodecyl sulfate (SDS) micelles, and in a mineral oil‐in‐water microemulsion stabilized by sodium cetyl sulfate (SCS) and 1‐pentanol. The triplet lifetimes are all in the range 7–9 μs. The rate constant for electron transfer quenching of triplet thionine by iron(II) is higher in the anionic media due to a higher local Fe2+ concentration. However, the back reaction between semithionine and iron(III) is not similarly enhanced in the presence of micelles or microemulsion. The dismutation of semithionine is a little slower in microemulsion than in water, but over two orders of magnitude slower in SDS micelles. The quantum yield of thionine triplet formation, determined for surfactant thionine in SCS microemulsion, approaches unity.

  DOI：

  10.1002/bbpc.19850890513

文献信息

• Kinetic study on the reversible hydride transfer between methylene blue and thionine
  作者：Yingjin Liu、Shunzo Yamamoto、Yoshimichi Fujiyama、Yoshimi Sueishi

  DOI：10.1039/b000046i

  日期：——

  The kinetics of the hydride transfer reaction between leuco methylene blue and thionine was investigated spectrophotometrically by means of the stopped-flow technique. Leuco methylene blue and leuco thionine were produced by photoreduction of methylene blue and thionine with triethylamine in ethanol in the drive syringe of the stopped-flow apparatus and their solutions were used as such in the measurement

  采用停流技术分光光度法研究了无色亚甲蓝和亚硫氨酸之间的氢化物转移反应动力学。无色亚甲蓝和无色亚硫氨酸是通过在停流装置的驱动注射器中用乙醇中的三乙胺光还原亚甲蓝和亚硫氨酸来制备的，并且它们的溶液原样用于反应速率的测量。发现该反应是可逆的，并获得了正向和反向反应的速率常数。kf/kb 的比率与平衡常数 (K) 的值一致，该平衡常数 (K) 是使用化学计量关系和守恒条件从平衡时亚甲蓝在 655 nm 处的吸光度获得的。
• Correlation of open-circuit voltage and short-circuit current of the totally illuminated, thin-layer iron-thionine photogalvanic cell with photostationary composition
  作者：Peter D. Wildes、Norman N. Lichtin

  DOI：10.1021/ja00489a004

  日期：1978.10
• Guha, S. N.; Naik, D. B.; Moorthy, P. N., Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1987, vol. 26, # 2, p. 99 - 101
  作者：Guha, S. N.、Naik, D. B.、Moorthy, P. N.

  DOI：——

  日期：——
• Microemulsions as photogalvanic cell fluids. The surfactant thionine-iron(II) system
  作者：N. S. Dixit、R. A. Mackay

  DOI：10.1021/j100220a027

  日期：1982.11

表征谱图