(5Z,8E,11E)-icosa-5,8,11-trienoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (5Z,8E,11E)-icosa-5,8,11-trienoic acid
• 化学式: C₂₀H₃₄O₂
• 分子量: 306.5
• InChiKey: UNSRRHDPHVZAHH-YDGTZJKXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  22
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] COMPOSITIONS AND METHODS OF DELIVERY OF DEUBIQUITINASE INHIBITORS<br/>[FR] COMPOSITIONS ET MÉTHODES D'ADMINISTRATION D'INHIBITEURS DE DÉUBIQUITINASE
  申请人：PHARMAKEA INC

  公开号：WO2015183987A1

  公开（公告）日：2015-12-03

  Described herein are compositions comprising deubiquitinase inhibitors in combination with albumin, methods of making such compositions, and methods of using such compositions in the treatment of conditions, diseases, or disorders that would benefit from inhibition of deubiquitinase activity.

  本文描述了含有去泛素化酶抑制剂与白蛋白组合的组合物，制备这种组合物的方法，以及利用这种组合物治疗需要抑制去泛素化酶活性的病症、疾病或紊乱的方法。
• Functional associative coatings for nanoparticles
  申请人：Hainfeld James F.

  公开号：US20080089836A1

  公开（公告）日：2008-04-17

  Described herein are nanoparticles that are coated with a bilayer of molecules formed from surface binding molecules and amphiphatic molecules. The bilayer coating self assembles on the nanoparticles from readily available materials/molecules. The modular design of the bilayer coated nanoparticles provides a means for readily and efficiently optimizing the properties of the bilayer coated nanoparticle compositions. Also described herein are uses of such nanoparticles in medicine, laboratory techniques, industrial and commerical applications.

  本文描述了一种纳米颗粒，其表面涂覆有由表面结合分子和两亲分子形成的双层分子层。该双层涂层可以自组装在纳米颗粒上，使用易得的材料/分子。双层涂层纳米颗粒的模块化设计提供了一种方便和高效地优化其性质的方法。此外，本文还描述了这种纳米颗粒在医学、实验室技术、工业和商业应用中的用途。
• Composition comprising an omega 9 series unsaturated fatty acid in the treatment of medical symptions caused by leucotriene B4
  申请人：SUNTORY LIMITED

  公开号：EP0635266A1

  公开（公告）日：1995-01-25

  A composition such as foods, drinks, pharmaceutical composition, for prevention or improvement of medical symptoms such as inflammation such as chronic inflammation, or allergy etc., comprising an omega 9 series unsaturated fatty acid such as 6,9-octadecadienoic acid, 8,11-eicosadienoic acid, 5,8,11-eicosatrienoic acid etc.

  一种用于预防或改善慢性炎症等炎症或过敏等医学症状的食品、饮料、药物组合物等组合物，包含欧米伽 9 系列不饱和脂肪酸，如 6,9-十八碳二烯酸、8,11-二十碳二烯酸、5,8,11-二十碳三烯酸等。
• Preventive or alleviating agent for medical symptoms caused by delayed allergy reactions
  申请人：SUNTORY LIMITED

  公开号：EP0704211A2

  公开（公告）日：1996-04-03

  A preventive or improving agent for medical symptoms accompanying delayed allergy reactions which contains an ω9-unsaturated fatty acid as an effective component is provided.

  提供了一种预防或改善伴随延迟性过敏反应出现的医学症状的制剂，它含有一种ω9-不饱和脂肪酸作为有效成分。
• PREVENTIVE OR REMEDY FOR DISEASES CAUSED BY ABNORMALITIES IN CARTILAGE TISSUES
  申请人：SUNTORY LIMITED

  公开号：EP0790056A1

  公开（公告）日：1997-08-20

  A preventive or remedy for diseases caused by abnormalities in cartilage tissues or a drink or food therefor which comprises as the active ingredient an omega-9 unsaturated fatty acid.

  一种预防或治疗软骨组织异常引起的疾病的药物或饮料或食品，其活性成分为欧米加-9 不饱和脂肪酸。