Ethanamine, 2,2'-oxybis-, acetate (1:2) | 1375090-12-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Ethanamine, 2,2'-oxybis-, acetate (1:2)
• 英文别名: acetic acid;2-(2-aminoethoxy)ethanamine
• CAS: 1375090-12-2
• 化学式: C8H20N2O5
• 分子量: 224.26
• InChiKey: SGCIOJPDUQHHDY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  136
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• METHODS FOR REDUCING AGGREGATE CONTENT IN PROTEIN PREPARATIONS
  申请人：Agency for Science, Technology and Research

  公开号：EP2953962A1

  公开（公告）日：2015-12-16
• CHROMATOGRAPHIC PURIFICATION OF ANTIBODIES FROM CHROMATIN-DEFICIENT CELL CULTURE HARVESTS
  申请人：Agency for Science, Technology and Research

  公开号：EP2961763A1

  公开（公告）日：2016-01-06
• US9975919B2
  申请人：——

  公开号：US9975919B2

  公开（公告）日：2018-05-22
• US9994611B2
  申请人：——

  公开号：US9994611B2

  公开（公告）日：2018-06-12
• [EN] Methods For Reducing Aggregate Content In Protein Preparations<br/>[FR] PROCÉDÉS DE RÉDUCTION DES AGRÉGATS DANS LES PRÉPARATIONS PROTÉINIQUES
  申请人：AGENCY SCIENCE TECH & RES

  公开号：WO2014123484A1

  公开（公告）日：2014-08-14

  A method of reducing aggregate and product-contaminant complex content in a protein preparation including a desired protein includes (i) contacting the protein preparation with at least one solid surface comprising at least one surface-bound ligand capable of binding a metal, the surface-bound ligand being capable of binding a metal is initially substantially devoid of a metal, the operating conditions are selected to substantially prevent the binding of the desired protein to the at least one solid surface and (ii) separating the protein preparation from the surface-bound ligand, such that when more than one surface- bound ligand is present, each surface-bound ligand is independently either of the same net charge or charge neutral.