2-Thiophenaldehyd-oxalyldihydrazon | 29816-37-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Thiophenaldehyd-oxalyldihydrazon
• 英文别名: oxalic acid bis-(thiophen-2-ylmethylene-hydrazide)；N'1,N'2-bis[(E)-thiophen-2-ylmethylidene]ethanedihydrazide；N,N'-bis(thiophen-2-ylmethylideneamino)oxamide
• CAS: 29816-37-3
• 化学式: C₁₂H₁₀N₄O₂S₂
• 分子量: 306.369
• InChiKey: GIISNKIPACLDIF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  139
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-Thiophenaldehyd-oxalyldihydrazon 、 zinc(II) chloride 以 乙醇 为溶剂， 以63%的产率得到N,N'-bis[(E)-thiophen-2-ylmethylideneamino]oxamide;dichlorozinc
  参考文献：
  名称：

  SYNTHESIS, CHARACTERIZATION, LIGATIONAL AND BIOLOGICAL PROPERTIES OF SOME ACYLHYDRAZINE DERIVED FURANYL AND THIENYL SCHIFF BASES WITH Co(II), Cu(II), Ni(II), AND Zn(II) METAL IONS

  摘要：

  Some acylhydrazine-derived furanyl and thienyl Schiff bases and their Co(II), Cu(II), Ni(II) and Zn(II) complexes have been prepared and characterized on the basis of their elemental analyses, magnetic moments, molar conductances and spectroscopic (electronic, IR, H-1 NMR and C-13 NMR) data. All of the Schiff base ligands function as tetradentates forming octahedral complexes with Co(11), Ni(11) and Zn(II) ions and a square-planar complex with Cu(H) ion. The ketonic form for the ligands L-1 and L-2 are the enolic form for the ligands L-3 and L-4 are preferred in the coordination. All of the ligands are biologically active and, in comparison, their metal complexes have shown higher bactericidal activity against one or more bacterial species such as Escherichia coli, Staphylococcus aureus, or Pseudomonas aeruginosa.

  DOI：

  10.1081/sim-100108267

文献信息

• SYNTHESIS, CHARACTERIZATION, LIGATIONAL AND BIOLOGICAL PROPERTIES OF SOME ACYLHYDRAZINE DERIVED FURANYL AND THIENYL SCHIFF BASES WITH Co(II), Cu(II), Ni(II), AND Zn(II) METAL IONS
  作者：Zahid H. Chohan、M. A. Farooq

  DOI：10.1081/sim-100108267

  日期：2001.11.30

  Some acylhydrazine-derived furanyl and thienyl Schiff bases and their Co(II), Cu(II), Ni(II) and Zn(II) complexes have been prepared and characterized on the basis of their elemental analyses, magnetic moments, molar conductances and spectroscopic (electronic, IR, H-1 NMR and C-13 NMR) data. All of the Schiff base ligands function as tetradentates forming octahedral complexes with Co(11), Ni(11) and Zn(II) ions and a square-planar complex with Cu(H) ion. The ketonic form for the ligands L-1 and L-2 are the enolic form for the ligands L-3 and L-4 are preferred in the coordination. All of the ligands are biologically active and, in comparison, their metal complexes have shown higher bactericidal activity against one or more bacterial species such as Escherichia coli, Staphylococcus aureus, or Pseudomonas aeruginosa.