(Acetyl-4-fluoroanilino)acetic acid | 618443-92-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (Acetyl-4-fluoroanilino)acetic acid
• 英文别名: 2-(N-acetyl-4-fluoroanilino)acetic acid
• CAS: 618443-92-8
• 化学式: C₁₀H₁₀FNO₃
• 分子量: 211.19
• InChiKey: JLPNGLJHJLOCCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  57.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• PRODUCTION OF ENANTIOMERICALLY PURIFIED AMINO ACIDS
  申请人：Baxter Scott

  公开号：US20140065679A1

  公开（公告）日：2014-03-06

  The present application relates to a mutated Amycoiatopsis sp. TS-1-60 NAAAR that shows improved activity of the enzyme compared with the wild type Amycoiatopsis sp. TS-1-60 NAAAR. The mutated NAAAR is almost five times more active than its wild type counterpart. The present application also relates to the use of mutated Amycoiatopsis sp. TS-1-60 NAAAR in the production of enantiomerically pure amino acid from its N-acyl derivative via dynamic kinetic resolution method.
• [EN] AGONISTS OF GPR131 AND USES THEREOF<br/>[FR] AGONISTES DE GPR131 ET LEURS UTILISATIONS
  申请人：METABOLEX INC

  公开号：WO2012174164A2

  公开（公告）日：2012-12-20

  Chemical compounds which act as agonists of, or otherwise modulate the activity of, GPR131 are disclosed. Related compositions, formulations and methods of use are also described.