tetrapropylammonium L-prolinate | 177722-39-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: tetrapropylammonium L-prolinate
• 英文别名: (2S)-pyrrolidine-2-carboxylate;tetrapropylazanium
• CAS: 177722-39-3
• 化学式: C₅H₈NO₂*C₁₂H₂₈N
• 分子量: 300.485
• InChiKey: OWAAZPCZDYPEFJ-VWMHFEHESA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.93
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  52.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  四丙基氢氧化铵 、 L-脯氨酸 以 水 为溶剂， 反应 2.0h， 生成 tetrapropylammonium L-prolinate
  参考文献：
  名称：

  N-Benzyloxycarbonylation of amines in the ionic liquid [TPA][l-Pro] as an efficient reaction medium

  摘要：

  An efficient method for the N-benzyloxycarbonylation of amines is described. The reaction of amines with Cbz-Cl in the ionic liquid [TPA][L-Pro] afforded the corresponding N-Cbz derivatives in excellent yields. The method is versatile for the preparation of a wide variety of N-Cbz derivatives of aliphatic and aromatic amines. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.02.108

文献信息

• N-Benzyloxycarbonylation of amines in the ionic liquid [TPA][l-Pro] as an efficient reaction medium
  作者：N. Suryakiran、K. Chinni Mahesh、D. Ramesh、J. Jon Paul Selvam、Y. Venkateswarlu

  DOI：10.1016/j.tetlet.2008.02.108

  日期：2008.4

  An efficient method for the N-benzyloxycarbonylation of amines is described. The reaction of amines with Cbz-Cl in the ionic liquid [TPA][L-Pro] afforded the corresponding N-Cbz derivatives in excellent yields. The method is versatile for the preparation of a wide variety of N-Cbz derivatives of aliphatic and aromatic amines. (C) 2008 Elsevier Ltd. All rights reserved.