2-[[5-[5-(3-phenyl-1H-indol-5-yl)furan-2-yl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 2-[[5-[5-(3-phenyl-1H-indol-5-yl)furan-2-yl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid
• 化学式: C₂₂H₁₆N₄O₃S
• 分子量: 416.5
• InChiKey: YOESMOXFSSIZOP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  133
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• [EN] SMALL MOLECULE INHIBITORS OF G PROTEIN COUPLED RECEPTOR 6 KINASE POLYPEPTIDES<br/>[FR] PETITES MOLÉCULES INHIBITRICES DE POLYPEPTIDES DE KINASES DES RÉCEPTEURS COUPLÉS AUX PROTÉINES G DE TYPE 6
  申请人：MAYO FOUNDATION

  公开号：WO2015164411A9

  公开（公告）日：2016-05-26
• SMALL MOLECULE INHIBITORS OF G PROTEIN COUPLED RECEPTOR 6 KINASES POLYPEPTIDES
  申请人：Mayo Foundation for Medical Education and Research

  公开号：US20170050979A1

  公开（公告）日：2017-02-23

  This document relates to inhibitors of G protein coupled receptor 6 kinase (GRK6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies, inflammation diseases, and autoimmune disorders.
• US9902739B2
  申请人：——

  公开号：US9902739B2

  公开（公告）日：2018-02-27
• [EN] SMALL MOLECULE INHIBITORS OF G PROTEIN COUPLED RECEPTOR 6 KINASES POLYPEPTIDES<br/>[FR] PETITES MOLÉCULES INHIBITRICES DE POLYPEPTIDES DE KINASES DES RÉCEPTEURS COUPLÉS AUX PROTÉINES G DE TYPE 6
  申请人：MAYO FOUNDATION

  公开号：WO2015164411A2

  公开（公告）日：2015-10-29

  This document relates to inhibitors of G protein coupled receptor 6 kinase (GRK6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies, inflammation diseases, and autoimmune disorders.