4-(1-Aminoaethyl)-cyclohexancarbonsaeure | 73846-00-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-(1-Aminoaethyl)-cyclohexancarbonsaeure
• 英文别名: 4-(1-Aminoethyl)-cyclo-hexanecarboxylic acid；4-(1-aminoethyl)cyclohexane-1-carboxylic acid
• CAS: 73846-00-1
• 化学式: C₉H₁₇NO₂
• 分子量: 171.239
• InChiKey: RPIJFLFNWQJSDV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(1-Aminoaethyl)-cyclohexancarbonsaeure 、 对甲苯磺酸一水合物 生成 4-(1-aminoethyl)cyclohexane-1-carboxylic acid;4-methylbenzenesulfonic acid
  参考文献：
  名称：

  ISODA SUMIRO; HIRATA MIYOSHI, CHEM. AND PHARM. BULL., 1979, 27, NO 11, 2735-2742

  摘要：

  DOI：
• 作为产物：
  描述：

  4-(1-aminoethyl)cyclohexane-1-carboxylic acid;4-methylbenzenesulfonic acid 以6%的产率得到
  参考文献：
  名称：

  ISODA SUMIRO; HIRATA MIYOSHI, CHEM. AND PHARM. BULL., 1979, 27, NO 11, 2735-2742

  摘要：

  DOI：

文献信息

• Molecular weight controller for polymerization of lactams to polyamides
  申请人：BASF Corporation

  公开号：EP0329105A2

  公开（公告）日：1989-08-23

  A molecular weight controller having particular application in the polymerization of a lactam, i.e., epsilon­caprolactam, to a polyamide, i.e., poly(epsiloncaprolactam). The molecular weight controller comprises a primary monofunctional amine, i.e., benzylamine, a primary monofunctional acid, i.e., acetic acid, and a salified aminoacid containing an aromatic, a cyclohexane, or cyclopentane moiety, i.e., 4-(aminomethylbenzoic acid salified with p-toluenesulfonic acid. The resulting polyamide has a reduced water extractable content.

  一种分子量控制器，特别适用于内酰胺（即epsiloncaprolactam）与聚酰胺（即 poly(epsiloncaprolactam)）的聚合。分子量控制剂包括初级单官能胺（即苄胺）、初级单官能酸（即乙酸）和含有芳香族、环己烷或环戊烷分子的盐化氨基酸（即用对甲苯磺酸盐化的 4-氨甲基苯甲酸）。所得聚酰胺的水萃取含量降低。
• 4-AMINO(ALKYL)CYCLOHEXANE-1-CARBOXAMIDE COMPOUND AND USE THEREOF
  申请人：YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD.

  公开号：EP0641781A1

  公开（公告）日：1995-03-08

  A 4-amino(alkyl)cyclohexane-1-carboxamide compound represented by general formula (I), an isomer thereof, and a pharmaceutically acceptable acid addition salt thereof, wherein each symbol is as defined in the specification. These substances have a remarkable, highly persistent and lowly toxic activity of increasing blood stream in coronary, cerebral, renal and peripheral arteries, and are useful as a potent and persistent hypotensive and a drug for preventing and treating diseases of a cardiovascular system such as coronary, cerebral, renal and peripheral arteries. Furthermore, they are useful as an antasthmatic, because they have activities of inhibiting experimental guinea pig asthma caused by the inhalation of histamine and inhibiting contraction of a specimen of an extirpated guinea pig trachea caused by acetylcholine.

  一种由通式(I)代表的 4-氨基(烷基)环己烷-1-甲酰胺化合物、其异构体及其药学上可接受的酸加成盐，其中各符号如说明书中所定义。这些物质在增加冠状动脉、脑动脉、肾动脉和外周动脉血流方面具有显著、高持久性和低毒性的活性，可用作强效持久的降压药以及预防和治疗冠状动脉、脑动脉、肾动脉和外周动脉等心血管系统疾病的药物。此外，它们还可用作抗哮喘药，因为它们具有抑制由吸入组胺引起的实验性豚鼠哮喘和抑制由乙酰胆碱引起的已切除豚鼠气管标本收缩的活性。
• Recycling and reuse of sulfonated polymer material in additive manufacturing
  申请人：Stratasys, Inc.

  公开号：US10982043B2

  公开（公告）日：2021-04-20

  A method of recycling and reusing a tap water-soluble sulfonated polymer material from a structural component made using an additive manufacturing process comprises dissolving the structural component in water to disperse the sulfonated polymer material into the water. The sulfonated polymer material is precipitated from the water and recovered; then dried and reformed into a form suitable for subsequent use as a consumable feedstock in a subsequent additive manufacturing process.

  一种回收和再利用自来水溶性磺化聚合物材料的方法，该材料来自使用添加剂制造工艺制造的结构组件，该方法包括将结构组件溶解在水中，使磺化聚合物材料分散到水中。磺化聚合物材料从水中析出并回收；然后干燥并重整成适合随后用作后续添加剂制造工艺中的消耗原料的形式。
• Water dispersible polymer for use in additive manufacturing
  申请人：Stratasys, Inc.

  公开号：US11186679B2

  公开（公告）日：2021-11-30

  A water dispersible sulfopolymer for use as a material in the layer-wise additive manufacture of a 3D part made of a non water dispersible polymer wherein the water dispersible polymer is a reaction product of a metal sulfo monomer, the water dispersible sulfo-polymer being dispersible in water resulting in separation of the water dispersible polymer from the 3D part made of the non water dispersible polymer.

  一种可在水中分散的硫基聚合物，可在由非水分散性聚合物制成的三维部件的分层添加制造中用作材料，其中水分散性聚合物是金属硫单体的反应产物，水分散性硫基聚合物可在水中分散，导致水分散性聚合物与由非水分散性聚合物制成的三维部件分离。
• Method for production of human tissue type plasminogen activator
  申请人：MITSUI TOATSU CHEMICALS, Inc.

  公开号：EP0366285B1

  公开（公告）日：1994-12-28