7-羟基-6H-苯并[c]色烯-6-酮 | 131086-90-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 中文名称: 7-羟基-6H-苯并[c]色烯-6-酮
• 英文名称: 7-hydroxy-6H-benzo[c]chromen-6-one
• 英文别名: 7-Hydroxy-6H-dibenzopyran-6-one；7-hydroxy-benzo[c]chromen-6-one；7-Hydroxy-benzo[c]chromen-6-on；7-hydroxy-6H-dibenzo[b,d]pyran-6-one；6H-Dibenzo(b,d)pyran-6-one, 7-hydroxy-；7-hydroxybenzo[c]chromen-6-one
• CAS: 131086-90-3
• 化学式: C₁₃H₈O₃
• 分子量: 212.205
• InChiKey: HPAOGQCLHJRYMC-UHFFFAOYSA-N

物化性质

• 熔点：
  122-123 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
• 沸点：
  414.1±24.0 °C(Predicted)
• 密度：
  1.395±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  7-羟基-6H-苯并[c]色烯-6-酮 在 四(三苯基膦)钯 吡啶 、 potassium phosphate 作用下， 以 1,4-二氧六环 、 二氯甲烷 为溶剂， 反应 22.0h， 生成 7-(4-methoxyphenyl)-6H-benzo[c]chromen-6-one
  参考文献：
  名称：

  1,3-双-甲硅烷基烯醇醚与苯并吡啶三氟甲磺酸酯的多米诺反应：高效合成荧光6H-苯并[c] chromen-6-one，二苯并[c，d] chromen-6-one和2,3-二氢-1H-4,6-dioxachrysen-5-ones。

  摘要：

  1，3-双甲硅烷基烯醇醚与苯并吡啶三氟甲磺酸酯的缩合反应是通过色酮与Me3SiOTf的反应原位生成的，提供了官能化的2，3-二氢苯并吡喃。用NEt 3或BBr 3处理后者会导致多米诺骨牌的迈克尔-迈克尔-醛缩内酰胺化反应，并形成多种7-羟基-6H-苯并[c] chromen-6-。通过使用Suzuki交叉偶联反应使羟基官能化。报道的方法学被应用于天然产物秋天水芹酚和一种新的荧光染料的合成，该荧光染料显示出有希望的光学性质。通过将色酮与包含一个偏氯基团的1,3-双甲硅烷基烯醇醚缩合，多米诺复古迈克尔-醛醇内酯化和苯甲酸酯化反应制得2,3-二氢-1H-4,6-二氧杂环戊烯-5-酮分子内威廉姆森反应。

  DOI：

  10.1002/chem.200501024
• 作为产物：
  描述：

  色酮 在 2,6-二甲基吡啶 、 盐酸 、 三乙胺 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 反应 25.0h， 生成 7-羟基-6H-苯并[c]色烯-6-酮
  参考文献：
  名称：

  Efficient synthesis of biaryl lactones by domino retro-Michael–aldol–lactonization reactions

  摘要：

  双芳基内酯通过2,3-二氢吡喃的独特多重反应——逆迈克尔反应-醇缩反应-内酯化反应制备而成。

  DOI：

  10.1039/b110236m

文献信息

• Synthesis and X-Ray Crystal Structure of Cynandione B Analogues
  作者：Lisa P. T. Hong、Jonathan M. White、Christopher D. Donner

  DOI：10.1071/ch11364

  日期：——

  The synthesis of analogues of cynandione B, a phenolic acetophenone from Cynanchum taiwanianum, is described. The one-step conversion of benzochromenones to the heptacyclic spiroacetal core of cynandione B using methylmagnesium bromide is investigated and structural requirements for this novel transformation established. X-ray crystal structure analysis has established the relative configuration in

  描述了来自台湾小辛的酚二酮苯乙二酮B的类似物的合成。研究了使用甲基溴化镁将苯并二氢吡喃酮单步转化为氰基二酮B的七环螺缩醛核心，并确定了这种新型转化的结构要求。X射线晶体结构分析已经确定了这些异常杂环中的相对构型。
• Synthesis of 7-hydroxydibenzopyran-6-ones <i>via</i> benzannulation of coumarins
  作者：H. Surya Prakash Rao、M. Prabakaran、Nandurka Muthanna

  DOI：10.1039/d2ob01203k

  日期：——

  We have successfully demonstrated a facile synthesis of a variety of 7-hydroxydibenzopyran-6-ones via a two-step protocol from 3-acylcoumarins having a latent Nazarov dienone functionality. Condensation of 3-acylcoumarins and ethyl cyanoacetate under basic (wet K2CO3) and microwave irradiation conditions followed by decarboethoxylative aromatization with Br2 or DDQ furnished dibenzopyran-6-ones in

  我们已经成功地证明了通过两步法从具有潜在纳扎罗夫二烯酮功能的 3-酰基香豆素中轻松合成各种 7-羟基二苯并吡喃-6-酮。3-酰基香豆素和氰基乙酸乙酯在碱性（湿 K 2 CO 3）和微波辐照条件下缩合，然后用 Br 2或 DDQ 脱碳乙氧基芳构化，以高产率提供二苯并吡喃-6-酮。C环的形成dibenzopyran-6-one 基序的主要依赖于活性亚甲基化合物和香豆素上的 C7 取代。二苯并吡喃-6-酮中的 Ar-Br 或 ArOTf 取代被用于钯催化的 Suzuki 与多种芳基硼酸偶联以增加结构多样性。C10 氰基二苯并吡喃-6-酮的还原脱氰提供了尿石素 A 的一些异构体。
• Process for producing a polymer by polymerization of a monomer having an ethylenic double bond
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：EP1063242A1

  公开（公告）日：2000-12-27

  A process for producing a polymer by polymerizing in a polymerization vessel a monomer having an ethylenic double bond is provided. In this process, the polymerization vessel has a polymer scale preventive coating film on its inner wall surfaces and other surfaces with which the monomer comes into contact during polymerization. The coating film is formed by coating a first coating liquid containing a compound selected from the group consisting of an aromatic compound having 5 or more conjugated π bonds and a heterocyclic compound having 5 or more conjugated π bonds and a second coating liquid containing at least one hydrophilic compound selected from the group consisting of a water-soluble polymeric compound, an inorganic colloid, an inorganic salt and an acid; the first coating liquid and the second coating liquid being simultaneously coated by means of steam as a carrier. This process can shorten the time for forming coating films of scale preventive agents to improve productivity, can improve the effect of preventing scales, can make colored particles less mix into polymer products obtained by this process, can lessen fish eyes and initial discoloring of formed products and can improve the quality of polymeric products and their formed or molded products.

  提供了一种通过在聚合容器中聚合具有乙烯双键的单体来生产聚合物的工艺。在该工艺中，聚合容器的内壁表面和聚合过程中单体接触的其他表面上有一层聚合物防垢涂膜。涂膜是通过涂覆第一涂覆液和第二涂覆液形成的，第一涂覆液含有一种选自具有 5 个或更多共轭 π 键的芳香族化合物和具有 5 个或更多共轭 π 键的杂环化合物的化合物，第二涂覆液含有至少一种选自水溶性高分子化合物、无机胶体、无机盐和酸的亲水性化合物；第一涂覆液和第二涂覆液通过蒸汽作为载体同时涂覆。这种工艺可以缩短防垢剂形成涂膜的时间以提高生产率，可以提高防垢效果，可以使有色颗粒较少地混入通过该工艺获得的聚合物产品中，可以减少成型产品的鱼眼和初始变色，可以提高聚合物产品及其成型或模塑产品的质量。
• Polymerisation process in a reactor with double coating against scale formation
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：EP1043338A1

  公开（公告）日：2000-10-11

  An improved process for producing a polymer by polymerizing a monomer having an ethylenic double bond in a polymerization vessel having a polymer scale preventive coating film on its inner wall surfaces, etc. is provided. The coating film is formed by coating a first coating liquid containing a compound selected from the group consisting of an aromatic compound having 5 or more conjugated π bonds and a heterocyclic compound having 5 or more conjugated π bonds, and then coating a second coating liquid a dye and/or pigment on the first layer. The first and second coating liquids are applied by means of steam as a carrier. The second layer has a surface having a contact angle to water of less than 60° after its surface has been kept in contact with a solution of mixture of water and a vinyl chloride monomer in a weight ratio of 1:1 at 50° C for 1 hour. This process can shorten the time for forming the coating film to improve productivity, can improve the effect of preventing adhesion of polymer scale, can make colored particles less mix into polymer products obtained by this process, can lessen fish eyes and initial discoloring of formed products and can improve the quality of polymeric products and their formed or molded products.

  本发明提供了一种通过在聚合容器中聚合具有乙烯双键的单体来生产聚合物的改进工艺，该聚合容器的内壁表面等处具有聚合物防垢涂膜。涂膜的形成方法是在第一层涂上含有选自具有 5 个或更多共轭 π 键的芳香族化合物和具有 5 个或更多共轭 π 键的杂环化合物的化合物的第一涂膜液，然后在第一层上涂上染料和/或颜料的第二涂膜液。第一种和第二种涂布液是以蒸汽为载体涂布的。第二层表面与水和氯乙烯单体重量比为 1:1 的混合物溶液在 50 摄氏度下接触 1 小时后，其表面与水的接触角小于 60°。这种工艺可以缩短涂膜的形成时间以提高生产率，可以提高防止聚合物鳞片附着的效果，可以使有色颗粒较少地混入通过这种工艺获得的聚合物产品中，可以减少成型产品的鱼眼和初期褪色，可以提高聚合物产品及其成型或模塑产品的质量。
• Image making medium
  申请人：——

  公开号：US20030035917A1

  公开（公告）日：2003-02-20

  The invention relates to an image support medium for creation of an aesthetic image that is an work or object for display. This support medium includes a polymer in an amount sufficient to enable the image to have at least one aesthetic element. In different embodiments, the image support medium is an image support stabilizer, the polymer is a synthetic absorbent or conductive polymer, or the polymer is a transparent or synthetic translucent polymer and a property of this transparent or translucent polymer is enhanced to facilitate the creation or preservation of the image by at least one stabilizer. The invention also relates to a method for preparing this image support medium. The method includes forming a reaction mixture comprising a monomer in an amount sufficient to provide or enable the image to have an aesthetic element, and processing the reaction mixture into a 2- or 3-dimensional shape.

  本发明涉及一种图像支持介质，用于创建作为作品或展示对象的美学图像。这种支撑介质包括一种聚合物，其用量足以使图像具有至少一种审美元素。在不同的实施例中，图像支持介质是一种图像支持稳定剂，聚合物是一种合成的吸收性或导电性聚合物，或者聚合物是一种透明或合成的半透明聚合物，并且这种透明或半透明聚合物的特性被至少一种稳定剂增强，以促进图像的创建或保存。本发明还涉及一种制备这种图像支持介质的方法。该方法包括形成由单体组成的反应混合物，其用量足以提供或使图像具有美学元素，并将反应混合物加工成 2 维或 3 维形状。