1-methoxy-3-(4-methoxy-N-methylanilino)propan-2-ol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-methoxy-3-(4-methoxy-N-methylanilino)propan-2-ol
• 化学式: C₁₂H₁₉NO₃
• 分子量: 225.28
• InChiKey: LOBJORACDSXKTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  41.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them
  申请人：KAO CORPORATION

  公开号：EP0761214A2

  公开（公告）日：1997-03-12

  Singlet oxygen quenchers containing as an active component a compound represented by the following formula (1) or (2): wherein each of R1, R2, R3, R4, R5, R10 and n are as described herein, and external compositions containing these compounds are provided for the prevention and treatment of various forms of damage to living bodies caused by singlet oxygen, and are thus quite useful as antiinflammation agents, anti-aging agents, agents preventing darkening of the skin, agents preventing protein denaturation, inhibitors against formation of sunburn cells, agents preventing lipid peroxidation, agents preventing DNA damage, and particularly in the fields of medicines and cosmetics as external compositions for the skin.

  单线态氧淬灭剂含有下式(1)或(2)所代表的化合物作为活性成分： 其中 R1、R2、R3、R4、R5、R10 和 n 均如本文所述，含有这些化合物的外用组合物可用于预防和治疗单线态氧对生物体造成的各种形式的损害，因此可用作抗炎剂、抗衰老剂、防止皮肤变黑的制剂、防止蛋白质变性的制剂、防止晒伤细胞形成的抑制剂、防止脂质过氧化的制剂、防止 DNA 损伤的制剂，特别是在医药和化妆品领域可用作皮肤外用组合物。
• US5709816A
  申请人：——

  公开号：US5709816A

  公开（公告）日：1998-01-20